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50例患者颈动脉支架植入术的随访及结果:初步报告

Carotid arterial stent implantation follow-up and results in 50 patients: preliminary report.

作者信息

Khosravi Alireza, Bideh Fereshteh Ziaee, Roghani Farshad, Saadatnia Mohammad, Khorvash Fariborz, Nejati Majid, Khoshpour Nastaran, Behjati Mohaddeseh

机构信息

Hypertension Research Center, Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Adjunct Professor, Department of Cardiology, Faculty of Medicine, Islamic Azad University, Yazd, Iran.

出版信息

Electron Physician. 2018 Feb 25;10(2):6400-6405. doi: 10.19082/6400. eCollection 2018 Feb.

DOI:10.19082/6400
PMID:29629065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5878036/
Abstract

BACKGROUND

Carotid artery stenting (CAS) is considered as a safe and effective procedure for treatment of carotid artery stenosis. Evaluation of this procedure's complications is essential for proper clinical decision-making.

OBJECTIVE

This study aimed to evaluate the cardiovascular events after CAS among our patients in Isfahan, Iran.

METHODS

This case-series study was conducted on fifty patients from December 2013 to May 2016. These patients were referred to the cardiology centers of Isfahan, Iran by a neurologist, for stenting of extracranial carotid arteries. The second step was examining the patients by cardiac interventionist. Stenting was performed on symptomatic patients with carotid artery stenosis of more than 50 percent or asymptomatic patients with more than 70 percent carotid artery stenosis on Doppler ultrasonography. Neurologic evaluation was performed at baseline, during hospital stay, and follow-up. Transient ischemic attack (TIA)/Stroke and Myocardial infarction (MI) questionnaires were filled out by a cardiologist over telephone interviews with the patients, for follow-up of one month, six months and at the end of study. Carotid Doppler ultrasonography was performed before and 6 months after stenting for evaluation of restenosis. Indeed, during the follow-up study, the major adverse cardiac events (MACE) were evaluated. All data were analyzed through SPSS v.17.

RESULTS

The mean age of patients was 70.73 (±14.01) years old (range: 48-89 years old). Composite endpoint of death, stroke, and MI was totally 8 percent. The rate of carotid arterial restenosis (Luminal arterial narrowing>50%) was 8%.

CONCLUSIONS

Despite the fact that carotid stenting is new in our center, our results can be compared to other important studies.

摘要

背景

颈动脉支架置入术(CAS)被认为是治疗颈动脉狭窄的一种安全有效的方法。评估该手术的并发症对于正确的临床决策至关重要。

目的

本研究旨在评估伊朗伊斯法罕我们的患者接受CAS后的心血管事件。

方法

本病例系列研究于2013年12月至2016年5月对50例患者进行。这些患者由神经科医生转诊至伊朗伊斯法罕的心脏病中心,进行颅外颈动脉支架置入术。第二步由心脏介入医生对患者进行检查。对有症状的颈动脉狭窄超过50%的患者或经多普勒超声检查显示颈动脉狭窄超过70%的无症状患者进行支架置入术。在基线、住院期间和随访时进行神经学评估。由心脏病专家通过与患者的电话访谈填写短暂性脑缺血发作(TIA)/中风和心肌梗死(MI)问卷,随访1个月、6个月和研究结束时。在支架置入术前和术后6个月进行颈动脉多普勒超声检查以评估再狭窄。实际上,在随访研究中,对主要不良心脏事件(MACE)进行了评估。所有数据通过SPSS v.17进行分析。

结果

患者的平均年龄为70.73(±14.01)岁(范围:48 - 89岁)。死亡、中风和心肌梗死的复合终点总计为8%。颈动脉再狭窄率(管腔动脉狭窄>50%)为8%。

结论

尽管颈动脉支架置入术在我们中心是新开展的,但我们的结果可与其他重要研究进行比较。

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