Hwang Jiyoung, Hong Seong Sook, Kim Hyun-Joo, Chang Yun-Woo, Nam Bo Da, Oh Eunsun, Lee EunJi, Cha Hwajin
1 Department of Radiology, Soonchunhyang University College of Medicine, Seoul Hospital , Seoul , Republic of Korea.
Br J Radiol. 2018 Jul;91(1087):20170864. doi: 10.1259/bjr.20170864. Epub 2018 Apr 16.
Diffusion-weighted imaging (DWI) with reduced field-of-view (FOV) has been shown to provide high spatial resolution with reduced distorsion in the spinal cord, breast, pancreas, and prostate gland. Therefore, we performed this study to evaluate the qualitative image quality and quantitative ADC value of reduced FOV DWI in patients with cervical cancer in comparison with conventional DWI.
This study retrospectively included 22 patients (mean age, 53.9 years) with biopsy-proven cervical cancer who underwent pelvic MR imaging including conventional DWI and reduced FOV DWI before therapy. Two observers independently rated image quality for reduced FOV DWI and conventional DWI regarding anatomic detail, lesion conspicuity, presence of artifacts, and overall image quality using the following 4-point scale. Quantitative analysis was performed by measuring the ADC value of the tumor. The Wilcoxon signed-rank test was used to compare qualitative scores and mean ADC value between two DWI sequences.
Reduced FOV DWI achieved significantly better anatomic detail, lesion conspicuity, presence of artifacts, and overall image quality compared to conventional DWI (p < 0.05). There was no significant difference in mean tumor ADC value between the two DWI sequences (0.990 × 10 mm s ± 0.364 at reduced FOV DWI vs 1.253 × 10 mm s ± 0.387 at conventional DWI) (p = 0.067).
Reduced FOV DWI shows better image quality in terms of anatomic detail and lesion conspicuity with fewer artifacts compared to conventional DWI. Advance in knowledge: Reduced FOV DWI may enhance diagnostic performance for evaluation of cervical cancer.
已证实，采用缩小视野（FOV）的扩散加权成像（DWI）可在脊髓、乳腺、胰腺和前列腺中提供高空间分辨率并减少图像失真。因此，我们开展本研究，以评估宫颈癌患者中缩小视野DWI与传统DWI相比的定性图像质量和定量表观扩散系数（ADC）值。
本研究回顾性纳入了22例经活检证实为宫颈癌的患者（平均年龄53.9岁），这些患者在治疗前接受了盆腔磁共振成像检查，包括传统DWI和缩小视野DWI。两名观察者使用以下4分制独立对缩小视野DWI和传统DWI的图像质量进行评分，内容包括解剖细节、病变清晰度、伪影情况和整体图像质量。通过测量肿瘤的ADC值进行定量分析。采用Wilcoxon符号秩检验比较两种DWI序列的定性评分和平均ADC值。
与传统DWI相比，缩小视野DWI在解剖细节、病变清晰度、伪影情况和整体图像质量方面均显著更好（p < 0.05）。两种DWI序列之间的平均肿瘤ADC值无显著差异（缩小视野DWI时为0.990×10⁻³mm²/s±0.364，传统DWI时为1.253×10⁻³mm²/s±0.387）（p = 0.067）。
与传统DWI相比，缩小视野DWI在解剖细节和病变清晰度方面显示出更好的图像质量，伪影更少。知识进展：缩小视野DWI可能会提高宫颈癌评估的诊断性能。
