a Institute of Child Health and Human Development, National Institutes of Health, University of the Philippines , Manila , Philippines.
b Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University , Bangkok , Thailand.
Hum Vaccin Immunother. 2018;14(8):2069-2074. doi: 10.1080/21645515.2018.1462068. Epub 2018 May 11.
Ring vaccinations create a zone of immune contacts around a case to prevent further disease transmission and have been successfully employed in the eradication of smallpox and the control of other infections. Millions of oral cholera vaccine (OCV) doses have been effectively deployed through mass vaccination campaigns. But there are situations when the OCV supply, resources, and time are limited and alternative strategies need to be considered. People living in close proximity of cholera cases often share risk factors such as contaminated water supply and poor sanitation. Targeting people within a given radius around a cholera case for intervention including vaccination, improved water supply and sanitation may be a practical and effective approach. A ring oral cholera vaccination strategy could be considered before, after or as an alternative to a mass vaccination approach. We review here the use of the ring vaccinations in general and specifically during cholera outbreaks.
环式疫苗接种在病例周围形成免疫接触区，以防止进一步的疾病传播，并已成功用于消灭天花和控制其他感染。数以百万计的口服霍乱疫苗（OCV）剂量已通过大规模疫苗接种运动有效部署。但是，存在 OCV 供应、资源和时间有限的情况，需要考虑替代策略。生活在霍乱病例附近的人通常具有共同的风险因素，如受污染的供水和卫生条件差。针对霍乱病例周围特定半径内的人群进行干预，包括接种疫苗、改善供水和卫生条件，可能是一种实用且有效的方法。在大规模疫苗接种之前、之后或作为替代方案，可以考虑采用环式口服霍乱疫苗接种策略。我们在这里回顾了环式疫苗接种的一般用途，特别是在霍乱疫情期间的用途。
