Key Laboratory of Resource Biology and Biotechnology in Western China, Northwest University, Ministry of Education, Xi'an 710069, PR China.
Key Laboratory of Resource Biology and Biotechnology in Western China, Northwest University, Ministry of Education, Xi'an 710069, PR China.
Int J Biol Macromol. 2018 Jul 15;114:1257-1266. doi: 10.1016/j.ijbiomac.2018.04.022. Epub 2018 Apr 7.
O. japonicus and L. spicata var. prolifera are distinguished as sources of highly promising yin-tonifying medicinals, namely Ophiopogonis Radix and Liriopes Radix. Liriopes Radix is generally medicinally used as a substitute for Ophiopogonis Radix in various prescriptions due to their extremely similar nature. Ophiopogonis Radix and Liriopes Radix are both very rich in bioactive polysaccharides, especially β‑fructans. Over the past twelve years, except for work on physical entrapment and chemical modification of obtained β‑fructans, the vast majority of studies are carried out to investigate the bioactivities of O. japonicus polysaccharides (OJP) and L. spicata var. prolifera polysaccharides (LSP), mainly including anti-diabetes, immunomodulation, anti-inflammation, antioxidation, anti-obesity, cardiovascular protection, etc. In addition, OJP and LSP are considered to have the potential to regulate intestinal flora. The main purpose of this review is to provide systematically reorganized information on structural characteristics and bioactivities of OJP and LSP to support their further therapeutic potentials and sanitarian functions.
黄精和节节草被区分开来，作为极具潜力的滋阴药材的来源，即麦冬和百合。由于它们的性质极其相似，百合通常在各种方剂中被用作麦冬的替代品。麦冬和百合都富含生物活性多糖，特别是β-果聚糖。在过去的十二年中，除了对获得的β-果聚糖进行物理包埋和化学修饰的研究外，绝大多数研究都致力于研究黄精多糖（OJP）和百合节节草变种多糖（LSP）的生物活性，主要包括抗糖尿病、免疫调节、抗炎、抗氧化、抗肥胖、心血管保护等。此外，OJP 和 LSP 被认为具有调节肠道菌群的潜力。本综述的主要目的是提供关于 OJP 和 LSP 的结构特征和生物活性的系统整理信息，以支持它们的进一步治疗潜力和卫生功能。
