West Brett J, Deng Shixin, Isami Fumiyuki, Uwaya Akemi, Jensen Claude Jarakae
Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA.
Research and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Foods. 2018 Apr 11;7(4):58. doi: 10.3390/foods7040058.
Noni juice is a globally popular health beverage originating in the tropics. Traditional Tahitian healers believe the noni plant to be useful for a wide range of maladies, and noni juice consumers throughout the world have similar perceptions. Nevertheless, human clinical trials are necessary for a precise understanding of what the health benefits of noni juice are. A review of published human intervention studies suggests that noni juice may provide protection against tobacco smoke-induced DNA damage, blood lipid and homocysteine elevation as well as systemic inflammation. Human intervention studies also indicate that noni juice may improve joint health, increase physical endurance, increase immune activity, inhibit glycation of proteins, aid weight management, help maintain bone health in women, help maintain normal blood pressure, and improve gum health. Further, these studies point to notable antioxidant activity in noni juice, more so than other fruit juices which served as trial placebos. It is this antioxidant effect and its interaction with the immune system and inflammation pathways that may account for many of the observed health benefits of noni juice. However, the existing evidence does have some limitations as far as its general application to noni juice products; all the peer-reviewed human interventions studies to date have involved only one source of French Polynesian noni juice. Geographical factors and variations in processing methods are known to produce commercial noni juice products with divergent phytochemical and nutrient compositions. Therefore, other sources of noni products may have different toxicological and pharmacological profiles.
诺丽果汁是一种源自热带地区、在全球广受欢迎的健康饮品。传统的塔希提岛治疗师认为诺丽植物对多种疾病都有疗效，世界各地饮用诺丽果汁的人也有类似的看法。然而，要准确了解诺丽果汁的健康益处，人体临床试验是必要的。对已发表的人体干预研究的综述表明，诺丽果汁可能对烟草烟雾引起的DNA损伤、血脂和同型半胱氨酸升高以及全身炎症具有保护作用。人体干预研究还表明，诺丽果汁可能改善关节健康、增强身体耐力、提高免疫活性、抑制蛋白质糖基化、有助于体重管理、帮助维持女性骨骼健康、帮助维持正常血压以及改善牙龈健康。此外，这些研究指出诺丽果汁具有显著的抗氧化活性，比用作试验安慰剂的其他果汁更为明显。正是这种抗氧化作用及其与免疫系统和炎症途径的相互作用，可能解释了诺丽果汁所观察到的许多健康益处。然而，就其对诺丽果汁产品的普遍适用性而言，现有证据确实存在一些局限性；迄今为止，所有经过同行评审的人体干预研究仅涉及一种法属波利尼西亚诺丽果汁来源。众所周知，地理因素和加工方法的差异会导致商业诺丽果汁产品的植物化学成分和营养成分各不相同。因此，其他诺丽产品来源可能具有不同的毒理学和药理学特征。
