Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France; CNRS, UMR 5557, Ecologie Microbienne, Villeurbanne, France, INRA, UMR1418, Villeurbanne, France.
Metapopulation Research Center, Department of Biosciences, University of Helsinki, Helsinki, Finland.
PLoS One. 2018 Apr 11;13(4):e0194521. doi: 10.1371/journal.pone.0194521. eCollection 2018.
The Asian tiger mosquito Aedes albopictus became of public health concern as it can replicate and transmit viral and filarial pathogens with a strong invasive success over the world. Various strategies have been proposed to reduce mosquito population's vectorial capacity. Among them, symbiotic control of mosquito borne disease offers promising perspectives. Such method is likely to be affected by the dynamics of mosquito-associated symbiotic communities, which might in turn be affected by host genotype and environment. Our previous study suggested a correlation between mosquitoes' origin, genetic diversity and midgut bacterial diversity. To distinguish the impact of those factors, we have been studying the midgut bacterial microbiota of two Ae. albopictus populations from tropical (La Réunion) and temperate (Montpellier) origins under controlled laboratory conditions. the two populations experienced random mating or genetic bottleneck. Microbiota composition did not highlight any variation of the α and β-diversities in bacterial communities related to host's populations. However, sizes of the mosquitoes were negatively correlated with the bacterial α-diversity of females. Variations in mosquito sex were associated with a shift in the composition of bacterial microbiota. The females' mosquitoes also exhibited changes in the microbiota composition according to their size and after experiencing a reduction of their genetic diversity. These results provide a framework to investigate the impact of population dynamics on the symbiotic communities associated with the tiger mosquito.
亚洲虎蚊（Aedes albopictus）因其具有较强的入侵能力，可以复制和传播病毒和丝虫病原体而引起了公众的健康关注。已经提出了各种策略来降低蚊子种群的媒介能力。其中，蚊子共生控制为蚊媒疾病的防治提供了有前景的视角。这种方法可能会受到蚊子共生群落动态的影响，而共生群落的动态又可能受到宿主基因型和环境的影响。我们之前的研究表明，蚊子的起源、遗传多样性和中肠细菌多样性之间存在相关性。为了区分这些因素的影响，我们一直在控制实验室条件下研究来自热带（留尼汪岛）和温带（蒙彼利埃）起源的两种白纹伊蚊种群的中肠细菌微生物群。这两个种群经历了随机交配或遗传瓶颈。微生物群组成并没有突出显示与宿主种群相关的细菌群落的 α 和 β 多样性的任何变化。然而，蚊子的大小与雌性细菌 α 多样性呈负相关。蚊子性别的变化与细菌微生物群组成的变化有关。雌性蚊子的微生物群组成也会根据其大小和遗传多样性的减少而发生变化。这些结果为研究种群动态对与虎蚊相关的共生群落的影响提供了一个框架。
