Hajar Tamar, Gontijo João Renato Vianna, Hanifin Jon M
Department of Dermatology, Oregon Health and Science University - Portland OR, USA.
An Bras Dermatol. 2018 Jan-Feb;93(1):104-107. doi: 10.1590/abd1806-4841.20187682.
Atopic dermatitis is a common inflammatory skin disease. New understanding in disease pathogenesis has led to a considerable number of promising new drugs in development. New topical agents can be especially helpful for children, providing an alternative to the need for chronic topical corticosteroid use. While many patients with mild or moderate disease can be managed with topical treatments, there are unmet needs for recalcitrant and severe cases. New and developing therapies hold promise for real advances in management of this complex disease.
特应性皮炎是一种常见的炎症性皮肤病。对疾病发病机制的新认识已催生出大量处于研发阶段的、前景可观的新药。新型外用药物对儿童可能特别有帮助,为避免长期使用外用糖皮质激素提供了一种替代方法。虽然许多轻中度患者可通过外用治疗得到控制,但顽固性和重度病例仍有未满足的需求。新的和正在研发的疗法有望在这种复杂疾病的治疗方面取得实质性进展。