Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong.
Affiliated Mental Health Center, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
Int J Geriatr Psychiatry. 2018 Jul;33(7):994-999. doi: 10.1002/gps.4883. Epub 2018 Apr 11.
To develop and examine the validity of a new brief cognitive test with less educational bias for screening cognitive impairment.
A new cognitive test, Hong Kong Brief Cognitive Test (HKBC), was developed based on review of the literature, as well as the views of an expert panel. Three groups of subjects aged 65 or above were recruited after written consent: normal older people recruited in elderly centres, people with mild NCD (neurocognitive disorder), and people with major NCD. The brief cognitive test, Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment Scale (MoCA), were administered to the subjects. The performance of HKBC in differentiating subjects with major NCD, mild NCD, and normal older people were compared with the clinical diagnosis, as well as the MMSE and MoCA scores.
In total, 359 subjects were recruited, with 99 normal controls, 132 subjects with major NCD, and 128 with mild NCD. The mean MMSE, MoCA, and HKBC scores showed significant differences among the 3 groups of subjects. In the receiving operating characteristic curve analysis of the HKBC in differentiating normal subjects from those with cognitive impairment (mild NCD + major NCD), the area under the curve was 0.955 with an optimal cut-off score of 21/22. The performances of MMSE and MoCA in differentiating normal from cognitively impaired subjects are slightly inferior to the HKBC.
The HKBC is a brief instrument useful for screening cognitive impairment in older adults and is also useful in populations with low educational level.
开发和检验一种新的、教育偏倚较小的简短认知测试，用于筛查认知障碍。
根据文献回顾以及专家小组的意见，开发了一种新的认知测试，即香港简短认知测试（HKBC）。在获得书面同意后，招募了三组年龄在 65 岁或以上的受试者：在老年人中心招募的正常老年人、轻度认知障碍（NCD）患者和重度认知障碍患者。对受试者进行简短认知测试、简易精神状态检查（MMSE）和蒙特利尔认知评估量表（MoCA）。比较了 HKBC 在区分重度 NCD、轻度 NCD 和正常老年人受试者方面的表现与临床诊断以及 MMSE 和 MoCA 评分。
共招募了 359 名受试者，其中 99 名为正常对照组，132 名为重度 NCD 患者，128 名为轻度 NCD 患者。3 组受试者的 MMSE、MoCA 和 HKBC 评分均有显著差异。在 HKBC 区分正常受试者与认知障碍（轻度 NCD+重度 NCD）受试者的接收者操作特征曲线分析中，曲线下面积为 0.955，最佳截断值为 21/22。MMSE 和 MoCA 在区分正常与认知障碍受试者方面的表现略逊于 HKBC。
HKBC 是一种用于筛查老年人认知障碍的简短工具，在教育程度较低的人群中也很有用。
