Department of Psychology, University of Amsterdam, Nieuwe Achtergracht 129-B, 1018 WS, Amsterdam, The Netherlands.
Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands.
Sci Rep. 2018 Apr 11;8(1):5854. doi: 10.1038/s41598-018-24224-2.
Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to fully capture this constitutional property. We propose community detection tools as a means to evaluate the complex network structure of psychopathology, free from its original boundaries of distinct disorders. Unique to this approach is that symptoms can belong to multiple communities. Using a large community sample and spanning a broad range of symptoms (Symptom Checklist-90-Revised), we identified 18 communities of interconnected symptoms. The differential role of symptoms within and between communities offers a framework to study the clinical concepts of comorbidity, heterogeneity and hallmark symptoms. Symptoms with many and strong connections within a community, defined as stabilizing symptoms, could be thought of as the core of a community, whereas symptoms that belong to multiple communities, defined as communicating symptoms, facilitate the communication between problem areas. We propose that defining symptoms on their stabilizing and/or communicating role within and across communities accelerates our understanding of these clinical phenomena, central to research and treatment of psychopathology.
网络理论作为一种理论和方法框架,正在激发许多研究领域的活力,其中包括临床心理学和精神病学。精神病理学网络理论的基础是特定症状及其相互作用的作用。然而,当前的统计工具未能完全捕捉到这种构成性质。我们提出社区检测工具作为评估精神病理学复杂网络结构的一种手段,不受其独特障碍的原始边界的限制。这种方法的独特之处在于,症状可以属于多个社区。使用大型社区样本并涵盖广泛的症状(Symptom Checklist-90-Revised),我们确定了 18 个相互关联的症状社区。症状在社区内和社区之间的不同作用为研究共病、异质性和标志性症状的临床概念提供了一个框架。在一个社区内具有许多和强大连接的症状,被定义为稳定症状,可以被认为是社区的核心,而属于多个社区的症状,被定义为沟通症状,促进了问题区域之间的沟通。我们提出,根据症状在社区内和跨社区中的稳定和/或沟通作用来定义症状,可以加速我们对这些临床现象的理解,这些现象是精神病理学研究和治疗的核心。