Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Division of Medical Neuroimaging Analysis, Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Sci Rep. 2018 Apr 11;8(1):5833. doi: 10.1038/s41598-018-24226-0.
Poor sleep quality is associated with unfavorable psychological measurements, whereas sleep duration has complex relationships with such measurements. The aim of this study was to identify the associations between microstructural properties of the brain and sleep duration/sleep quality in a young adult. The associations between mean diffusivity (MD), a measure of diffusion tensor imaging (DTI), and sleep duration/sleep quality were investigated in a study cohort of 1201 normal young adults. Positive correlations between sleep duration and MD of widespread areas of the brain, including the prefrontal cortex (PFC) and the dopaminergic systems, were identified. Negative correlations between sleep quality and MD of the widespread areas of the brain, including the PFC and the right hippocampus, were also detected. Lower MD has been previously associated with more neural tissues in the brain. Further, shorter sleep duration was associated with greater persistence and executive functioning (lower Stroop interference), whereas good sleep quality was associated with states and traits relevant to positive affects. These results suggest that bad sleep quality and longer sleep duration were associated with aberrant neurocognitive measurements in the brain in healthy young adults.
睡眠质量差与不良的心理测量结果有关，而睡眠时间与这些测量结果的关系则较为复杂。本研究旨在探讨脑微观结构特性与年轻成年人睡眠时间/睡眠质量之间的关系。在一项由 1201 名正常年轻成年人组成的研究队列中，研究了平均弥散度（MD）与弥散张量成像（DTI）之间的关系，MD 是一种测量扩散张量成像的指标。研究发现，睡眠时间与大脑广泛区域（包括前额叶皮质和多巴胺能系统）的 MD 呈正相关。睡眠质量与大脑广泛区域（包括前额叶皮质和右海马体）的 MD 呈负相关。较低的 MD 与大脑中更多的神经组织有关。此外，较短的睡眠时间与更大的坚持性和执行功能（较低的斯特鲁普干扰）相关，而良好的睡眠质量与与积极影响相关的状态和特质相关。这些结果表明，在健康的年轻成年人中，睡眠质量差和睡眠时间长与大脑中异常的神经认知测量结果有关。
