Chopra Ajay, Mitra Debdeep, Sharma Loknandini, Agarwal Reetu
Department of Dermatology, Base Hospital, Delhi Cantt, New Delhi, India.
Indian Dermatol Online J. 2018 Mar-Apr;9(2):117-119. doi: 10.4103/idoj.IDOJ_162_17.
We report the case of a 32-year- old man with a short 3-week history of erythematous, annular, non scaly plaques on palmar and dorsal aspect of his hands, who was concurrently diagnosed as a case of sarcoidosis on the basis of findings of generalized lymphadenopathy and radiological and histological features of pulmonary sarcoidosis. His skin biopsy was consistent with the diagnosis of granuloma annulare. Sarcoidosis and granuloma annulare are two separate diseases, which involve the skin and have a mononuclear histiocytic cellular reaction, although their aetiology is still unknown. Granuloma annulare has been associated with the concomitant diagnosis of sarcoidosis in only two more case reports and this association can be evaluated further to study a common link in the aetipathogenesis of these two granulomatous skin diseases.
我们报告了一例32岁男性病例,其双手掌侧和背侧出现红斑性、环状、无鳞屑斑块,病程仅3周。基于全身淋巴结肿大以及肺部结节病的影像学和组织学特征,该患者同时被诊断为结节病。其皮肤活检结果符合环状肉芽肿的诊断。结节病和环状肉芽肿是两种不同的疾病,均累及皮肤且有单核组织细胞反应,尽管它们的病因尚不清楚。环状肉芽肿仅在另外两份病例报告中与结节病的同时诊断相关,这种关联可进一步评估,以研究这两种肉芽肿性皮肤病发病机制中的共同联系。