Effect of niacin/nicotinamide deficiency on the diabetogenic effect of streptozotocin.
作者信息
Wright J R, Mendola J, Lacy P E
机构信息
Department of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110.
出版信息
Experientia. 1988 Jan 15;44(1):38-40. doi: 10.1007/BF01960237.
PMID:2965027
Abstract
Weanling CD-1 mice were fed either a control diet or a diet deficient in niacin/nicotinamide for one month and then injected i.v. with 60, 80, 100, 120, 140, or 160 mg/kg streptozotocin. Mice on the deficient diet developed a higher incidence of diabetes and more severe hyperglycemia than those on the control diet.
摘要
Zotero 插件