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电针对治疗膝骨关节炎疼痛的影响。

Tackling Osteoarthritic Knee Pain with Electroacupuncture.

机构信息

Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.

出版信息

Chin J Integr Med. 2018 Nov;24(11):803-805. doi: 10.1007/s11655-018-2929-3. Epub 2018 Apr 12.

DOI:10.1007/s11655-018-2929-3
PMID:29651675
Abstract

Electroacupuncture (EA) has been widely used in pain relief. Clinical evidence has revealed its unique advantages and effectiveness in alleviating pain. Studies on EA and pain relief have revealed that EA displays greater analgesic effects for different types of pain in comparison to manual acupuncture. Here, we reviewed the clinical application and mechanism of EA in treating osteoarthritic knee pain and its influence factors in curative effect.

摘要

电针（EA）在缓解疼痛方面得到了广泛应用。临床证据显示，它在缓解疼痛方面具有独特的优势和疗效。EA 与疼痛缓解相关的研究表明，与手动针灸相比，EA 对不同类型的疼痛具有更大的镇痛效果。在此，我们回顾了 EA 在治疗膝骨关节炎疼痛中的临床应用和机制及其疗效影响因素。

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1
Tackling Osteoarthritic Knee Pain with Electroacupuncture.电针对治疗膝骨关节炎疼痛的影响。
Chin J Integr Med. 2018 Nov;24(11):803-805. doi: 10.1007/s11655-018-2929-3. Epub 2018 Apr 12.
2
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J Altern Complement Med. 2003 Oct;9(5):641-9. doi: 10.1089/107555303322524490.
3
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The electroacupuncture-induced analgesic effect mediated by 5-HT1, 5-HT3 receptor and muscarinic cholinergic receptors in rat model of collagenase-induced osteoarthritis.在胶原酶诱导的骨关节炎大鼠模型中，电针诱导的镇痛作用由5-羟色胺1、5-羟色胺3受体和毒蕈碱型胆碱能受体介导。
BMC Complement Altern Med. 2016 Jul 13;16:212. doi: 10.1186/s12906-016-1204-z.
5
Immediate effects of electroacupuncture and manual acupuncture on pain, mobility and muscle strength in patients with knee osteoarthritis: a randomised controlled trial.电针和手动针刺对膝骨关节炎患者疼痛、活动度和肌肉力量的即时影响：一项随机对照试验。
Acupunct Med. 2014 Jun;32(3):236-41. doi: 10.1136/acupmed-2013-010489. Epub 2014 Feb 24.
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A rat model of knee osteoarthritis suitable for electroacupuncture study.一种适用于电针研究的膝关节骨关节炎大鼠模型。
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[Clinical observation on the therapeutic effect of drugs-paste separated moxibustion combined with electroacupunture for knee osteoarthritis patients of cold-damp type].药物贴隔灸联合电针治疗寒湿型膝骨关节炎患者的疗效临床观察
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[Repair effects of close-to-bone needing combined with electroacupuncture on extracellular matrix of cartilage in rabbits with knee osteoarthritis].贴骨需求联合电针对膝骨关节炎兔软骨细胞外基质的修复作用
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引用本文的文献

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Efficacy of acupuncture combined with active exercise training in improving pain and function of knee osteoarthritis individuals: a systematic review and meta-analysis.针灸结合主动运动训练改善膝骨关节炎患者疼痛和功能的疗效：系统评价和荟萃分析。
J Orthop Surg Res. 2023 Dec 2;18(1):921. doi: 10.1186/s13018-023-04403-2.
2
Electroacupuncture as an Adjuvant Approach to Rehabilitation during Postacute Phase after Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.电针作为全膝关节置换术后急性期后康复的辅助方法：随机对照试验的系统评价和荟萃分析
Evid Based Complement Alternat Med. 2021 Jul 27;2021:9927699. doi: 10.1155/2021/9927699. eCollection 2021.
3

本文引用的文献

1
Electroacupuncture serum inhibits TNF‑α‑mediated chondrocyte inflammation via the Ras‑Raf‑MEK1/2‑ERK1/2 signaling pathway.电针对 TNF-α 介导的软骨细胞炎症的抑制作用是通过 Ras-Raf-MEK1/2-ERK1/2 信号通路实现的。
Mol Med Rep. 2017 Nov;16(5):5807-5814. doi: 10.3892/mmr.2017.7366. Epub 2017 Aug 28.
2
Electro-Acupuncture is Beneficial for Knee Osteoarthritis: The Evidence from Meta-Analysis of Randomized Controlled Trials.电针治疗膝骨关节炎的疗效观察：基于随机对照试验的 Meta 分析。
Am J Chin Med. 2017;45(5):965-985. doi: 10.1142/S0192415X17500513. Epub 2017 Jun 28.
3
Comparing the Effectiveness of Electroacupuncture with Different Grades of Knee Osteoarthritis: A Prospective Study.
Prospective, Single-Center Comparison of Transcranial Direct Current Stimulation Plus Electroacupuncture and Standard Analgesia in Patients After Total Knee Arthroplasty: Effect on Rehabilitation and Functional Recovery.
经颅直流电刺激联合电针对全膝关节置换术后患者的影响：对康复和功能恢复的前瞻性、单中心比较。
Med Sci Monit. 2021 Jun 9;27:e930363. doi: 10.12659/MSM.930363.
4
Electroacupuncture Delays Cartilage Degeneration by Modulating Nuclear Factor-κB Signaling Pathway.电针对软骨退变的作用机制：调控核因子-κB 信号通路。
Chin J Integr Med. 2019 Sep;25(9):677-683. doi: 10.1007/s11655-018-2916-8. Epub 2019 Jan 17.
比较不同分级膝关节骨关节炎电针治疗的有效性：一项前瞻性研究。
Cell Physiol Biochem. 2016;39(6):2331-2340. doi: 10.1159/000447925. Epub 2016 Nov 11.
4
The electroacupuncture-induced analgesic effect mediated by 5-HT1, 5-HT3 receptor and muscarinic cholinergic receptors in rat model of collagenase-induced osteoarthritis.在胶原酶诱导的骨关节炎大鼠模型中，电针诱导的镇痛作用由5-羟色胺1、5-羟色胺3受体和毒蕈碱型胆碱能受体介导。
BMC Complement Altern Med. 2016 Jul 13;16:212. doi: 10.1186/s12906-016-1204-z.
5
Electroacupuncture with different current intensities to treat knee osteoarthritis: a single-blinded controlled study.不同电流强度电针治疗膝骨关节炎：一项单盲对照研究。
Int J Clin Exp Med. 2015 Oct 15;8(10):18981-9. eCollection 2015.
6
Repeated verum but not placebo acupuncture normalizes connectivity in brain regions dysregulated in chronic pain.重复进行真针灸而非假针灸可使慢性疼痛中失调的脑区连接恢复正常。
Neuroimage Clin. 2015 Sep 25;9:430-5. doi: 10.1016/j.nicl.2015.09.012. eCollection 2015.
7
Electroacupuncture inhibits chronification of the acute pain of knee osteoarthritis: study protocol for a randomized controlled trial.电针抑制膝关节骨关节炎急性疼痛的慢性化：一项随机对照试验的研究方案
Trials. 2015 Apr 1;16:131. doi: 10.1186/s13063-015-0636-y.
8
Pain management with acupuncture in osteoarthritis: a systematic review and meta-analysis.针灸治疗骨关节炎疼痛的管理：系统评价和荟萃分析。
BMC Complement Altern Med. 2014 Aug 23;14:312. doi: 10.1186/1472-6882-14-312.
9
[Effects of acupotomy, electroacupuncture or round-sharp acupuncture needle interventions on expression of Bcl-2, Bax, Caspase-3 proteins of rectus femoris in rabbits with knee ostarthritis].[针刀、电针或圆利针干预对膝骨关节炎家兔股直肌Bcl-2、Bax、Caspase-3蛋白表达的影响]
Zhen Ci Yan Jiu. 2014 Apr;39(2):100-5, 123.
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Immediate effects of electroacupuncture and manual acupuncture on pain, mobility and muscle strength in patients with knee osteoarthritis: a randomised controlled trial.电针和手动针刺对膝骨关节炎患者疼痛、活动度和肌肉力量的即时影响：一项随机对照试验。
Acupunct Med. 2014 Jun;32(3):236-41. doi: 10.1136/acupmed-2013-010489. Epub 2014 Feb 24.