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乙烯-乙烯醇共聚物在经皮和血管内治疗 Ia 型内漏中与其他栓塞剂联合应用的作用。

The role of ethylene-vinyl alcohol copolymer in association with other embolic agents for the percutaneous and endovascular treatment of type Ia endoleak.

机构信息

Diagnostic and Interventional Radiology Department, San Paolo Hospital, University of Milan, Milan, Italy.

Vascular Surgery Department, University of Insubria, Viale Borri, 57, 21100, Varese, VA, Italy.

出版信息

Radiol Med. 2018 Aug;123(8):638-642. doi: 10.1007/s11547-018-0885-4. Epub 2018 Apr 13.

Abstract

AIM

To evaluate safety, technical and clinical success of embolization of type Ia endoleak (T1a EL) using ethylene-vinyl alcohol copolymer as embolic agent alone or in combination with other materials.

MATERIALS AND METHODS

Five patients presented T1a EL after endovascular repair of aortic aneurysms (EVAR) with radiological evidence of expanding sac size; in particular, three had contained rupture. In one patient, proximal cuff insertion was previously performed, in three patients proximal cuff was urgently inserted but T1a EL persisted; one patient, previously treated with Ovation Abdominal Stent Graft System, was directly proposed for endovascular treatment. In all cases, endovascular embolization was successfully performed and the transfemoral approach was always chosen; in one case it failed and translumbar approach by direct puncture of the sac was required. Used embolization agents were glue, ethylene-vinyl alcohol copolymer (Onyx) and coils in three cases, n-butyl cyanoacrylate and Onyx in one case, Onyx and coils in the last case.

RESULTS

Technical success rate was 100% as well as clinical success. No major or minor complication, including non-target embolization, was registered. Clinical success was 100% until today and the sac diameter remained stable in four patients and decreased in one.

CONCLUSIONS

Onyx may be considered a suitable embolic agent in the treatment of patients with type Ia endoleaks after EVAR, after failure of conventional treatments such as prolonged balloon inflation of the aortic neck or deployment of large bare stent.

摘要

目的

评估单独使用乙烯-乙烯醇共聚物或联合其他材料栓塞Ⅰa 型内漏(T1a EL)的安全性、技术和临床成功率。

材料和方法

5 名患者在接受腹主动脉瘤血管内修复(EVAR)后出现 T1a EL,影像学显示瘤囊增大;其中 3 例有破裂。1 例患者先前进行了近端套袖插入,3 例患者紧急进行了近端套袖插入,但 T1a EL 仍持续存在;1 例患者先前使用 Ovation 腹主动脉支架系统治疗,直接提出进行血管内治疗。所有患者均成功进行了血管内栓塞,且均选择经股动脉入路;1 例患者经股动脉入路失败,需要通过直接穿刺瘤囊进行经皮穿刺入路。使用的栓塞剂包括 3 例患者的胶、乙烯-乙烯醇共聚物(Onyx)和线圈,1 例患者的 n-丁基氰基丙烯酸酯和 Onyx,最后 1 例患者的 Onyx 和线圈。

结果

技术成功率和临床成功率均为 100%。未发生主要或次要并发症,包括非目标栓塞。截至目前,临床成功率为 100%,4 例患者瘤囊直径保持稳定,1 例患者瘤囊直径减小。

结论

在 EVAR 后常规治疗(如主动脉颈部长时间球囊扩张或大裸支架置入)失败的情况下,Onyx 可作为治疗Ⅰa 型内漏的一种合适的栓塞剂。

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