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Scalable Spatial-Spectral Multiplexing of Single-Virus Detection Using Multimode Interference Waveguides.基于多模干涉波导的单病毒检测的可扩展空间-光谱多路复用。
Sci Rep. 2017 Sep 22;7(1):12199. doi: 10.1038/s41598-017-12487-0.
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On-chip wavelength multiplexed detection of cancer DNA biomarkers in blood.血液中癌症DNA生物标志物的芯片上波长复用检测。
Biomicrofluidics. 2016 Dec 15;10(6):064116. doi: 10.1063/1.4968033. eCollection 2016 Nov.
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Signal-to-noise Enhancement in Optical Detection of Single Viruses with Multi-spot Excitation.多光斑激发用于单病毒光学检测中的信噪比增强
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Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):12933-7. doi: 10.1073/pnas.1511921112. Epub 2015 Oct 5.
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Hollow waveguides with low intrinsic photoluminescence fabricated with Ta(2)O(5) and SiO(2) films.采用Ta(2)O(5)和SiO(2)薄膜制备的具有低本征光致发光特性的中空波导。
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Optofluidic waveguides: I. Concepts and implementations.光流控波导:I. 概念与实现
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Hollow ARROW Waveguides on Self-Aligned Pedestals for Improved Geometry and Transmission.用于改善几何形状和传输的自对准基座上的空心ARROW波导
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Principles and application of reduced beat length in MMI couplers.MMI 耦合器中缩短拍长的原理与应用
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Compact silicon-on-insulator-based multimode interference coupler with bilevel taper structure.具有双级锥形结构的基于绝缘体上硅的紧凑型多模干涉耦合器。
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用于光流体复用的高保真激发模式的基于优化ARROW的MMI波导

Optimized ARROW-Based MMI Waveguides for High Fidelity Excitation Patterns for Optofluidic Multiplexing.

作者信息

Stott Matthew A, Ganjalizadeh Vahid, Olsen Maclain, Orfila Marcos, McMurray Johnny, Schmidt Holger, Hawkins Aaron R

机构信息

Department of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602 USA.

School of Engineering, University of California Santa Cruz, Santa Cruz, CA 95064 USA.

出版信息

IEEE J Quantum Electron. 2018 Jun;54(3). doi: 10.1109/JQE.2018.2816120. Epub 2018 Mar 15.

DOI:10.1109/JQE.2018.2816120
PMID:29657333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5892433/
Abstract

Multimode interference (MMI) waveguides can be used for multiplexing and de-multiplexing optical signals. High fidelity, wavelength dependent multi-spot patterns from MMI waveguides are useful for sensitive and simultaneous identification of multiple targets in multiplexed fluorescence optofluidic biosensors. Through experiments and simulation, this paper explores design parameters for an MMI rib anti-resonant reflecting optical waveguide (ARROW) in order to produce high fidelity spot patterns at the liquid core biomarker excitation region. Width and etch depth of the single excitation rib waveguide used to excite the MMI waveguide are especially critical because they determine the size of the input optical mode which is imaged at the MMI waveguide's output. To increase optical throughput into the MMI waveguide when light is coupled in from an optical fiber, tapers in the waveguide width can be used for better mode matching.

摘要

多模干涉(MMI)波导可用于光信号的复用和解复用。MMI波导产生的高保真、波长相关的多点图案,对于在复用荧光光流体生物传感器中灵敏且同时地识别多个目标很有用。通过实验和模拟,本文探索了MMI肋形抗谐振反射光波导(ARROW)的设计参数,以便在液芯生物标志物激发区域产生高保真光斑图案。用于激发MMI波导的单个激发肋形波导的宽度和蚀刻深度尤为关键,因为它们决定了在MMI波导输出端成像的输入光模式的大小。当光从光纤耦合进入MMI波导时,为了提高光通量,可使用波导宽度渐变来实现更好的模式匹配。