多囊卵巢综合征女性的健康饮食指数：一项病例对照研究。
Healthy eating index in women with polycystic ovary syndrome: A case-control study.
作者信息
Hosseini Mahbobeh Sadat, Dizavi Alireza, Rostami Hosein, Parastouei Karim, Esfandiari Saeed
机构信息
Clinical Research Development Unit, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Int J Reprod Biomed. 2017 Sep;15(9):575-582.
BACKGROUND
Despite many effort to identify and control the factors involved in polycystic ovary syndrome (PCOS), there are no available reports indicating the association of healthy eating index (HEI) and PCOS.
OBJECTIVE
The present study has been conducted to examine the relationship between HEI and PCOS.
MATERIALS AND METHODS
In this case-control study, the study population comprised 297 women aged 20-40 yr referred to Baqiyatallah Hospital Clinics, Tehran, Iran in two groups: case group (n=99) and control group (n=198). The usual dietary data were collected using a validated 168-item semi-quantitative food frequency questionnaire. Standard anthropometric measurements (height, weight, and waist circumference) were also taken. Unconditional logistic regression was used to analyze the relationship between the PCOS and the HEI.
RESULTS
The mean age and body mass index of case and control groups were 29±5.5 vs. 29.5±6 yr and 26.6±4.8 vs. 26±4.2 kg/m², respectively (p=0.752, p=0.822). Mean HEI scores for the case and control groups were found to be 61 and 65, respectively. In final model and after adjustment for confounders, the prevalence of PCOS in subjects in the highest tertile HEI score was significantly (50%) less than those in the lowest tertile HEI score (OR=0.50; 95% CI: 0.25-0.74, p=0.001).
CONCLUSION
Our results suggest that HEI score is inversely associated with the risk of PCOS in adult women.
背景
尽管人们为识别和控制多囊卵巢综合征（PCOS）相关因素付出了诸多努力，但尚无报告表明健康饮食指数（HEI）与PCOS之间存在关联。
目的
本研究旨在探讨HEI与PCOS之间的关系。
材料与方法
在这项病例对照研究中，研究对象为297名年龄在20至40岁之间的女性，她们被转诊至伊朗德黑兰的巴基耶塔拉医院诊所，分为两组：病例组（n = 99）和对照组（n = 198）。使用经过验证的168项半定量食物频率问卷收集日常饮食数据。还进行了标准人体测量（身高、体重和腰围）。采用无条件逻辑回归分析PCOS与HEI之间的关系。
结果
病例组和对照组的平均年龄分别为29±5.5岁和29.5±6岁，体重指数分别为26.6±4.8kg/m²和26±4.2kg/m²（p = 0.752，p = 0.822）。病例组和对照组的平均HEI得分分别为61分和65分。在最终模型中，在对混杂因素进行调整后，HEI得分最高三分位数的受试者中PCOS的患病率显著低于HEI得分最低三分位数的受试者（50%）（OR = 0.50；95%CI：0.25 - 0.74，p = 0.001）。
结论
我们的结果表明，HEI得分与成年女性患PCOS的风险呈负相关。
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