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在麻醉期间使用潮气量通气机对儿童进行人工通气。

Artificial ventilation in children during anaesthesia using a tidal volume ventilator.

作者信息

Lindahl S, Okmian L, Thomson D

出版信息

Acta Anaesthesiol Scand. 1979 Dec;23(6):587-95. doi: 10.1111/j.1399-6576.1979.tb01491.x.

Abstract

Standards for artificial pulmonary ventilation at ventilatory frequencies of 15 and 20 cycles per min, (PETCO2 4 +/- 0.5 kPa), were defined in 16 children with healthy lungs and body weights between 2.6 and 22.6 kg. A tidal volume ventilator and balanced anaesthesia were used during abdominal surgery. At f = 20 cycles/min an approximately direct proportionality existed between tidal volume and body weight (VTpat = 12.3 . kg b.w.--2.1, r = 0.99). The mean value VTpat per kg b.w. was 12.1 +/- 1.4 ml/kg. At f = 15 cycles/min, a linear relationship between tidal volume and kg b.w. was recorded (VTpat = 14.6 . kg b.w. + 16, r = 0.97). The mean value VTpat per kg b.w. was 15.9 +/- 1.5 ml/kg. A significant decrease in total compliance was recorded during the initial part of the surgical procedure. A rectilinear relationship existed between total compliance and kg b.w. (CTOT = 11.2 . kg b.w.--12.5, r = 0.95). The mean value CTOT per kg b.w. was 9.7 +/- 0.54 ml/kPa/kg at f = 20. The endotracheal peak pressure maintained a fairly constant pressure level independent of the initial pressure within the ventilator, the tidal volume and the body weight, a phenomenon explained by the hypothesis that the proportional increase in total lung volume and functional residual capacity in the older children compensated for the higher pressures.

摘要

对16名肺部健康、体重在2.6至22.6千克之间的儿童,定义了每分钟通气频率为15次和20次(呼气末二氧化碳分压4±0.5千帕)时的人工肺通气标准。腹部手术期间使用潮气量通气机和平衡麻醉。在f = 20次/分钟时,潮气量与体重之间存在近似直接比例关系(VTpat = 12.3×体重 - 2.1,r = 0.99)。每千克体重的VTpat平均值为12.1±1.4毫升/千克。在f = 15次/分钟时,记录到潮气量与千克体重之间呈线性关系(VTpat = 14.6×体重 + 16,r = 0.97)。每千克体重的VTpat平均值为15.9±1.5毫升/千克。在手术过程开始阶段,总顺应性显著下降。总顺应性与千克体重之间存在直线关系(CTOT = 11.2×体重 - 12.5,r = 0.95)。在f = 20时,每千克体重的CTOT平均值为9.7±0.54毫升/千帕/千克。气管内峰值压力保持相当恒定的压力水平,与通气机内的初始压力、潮气量和体重无关,这一现象可由以下假设解释:年龄较大儿童肺总量和功能残气量的成比例增加补偿了较高的压力。

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