Matsunaga K, Hosokawa K, Suzuki M, Arima Y, Hayakawa R
Division of Dermatology, Nagoya University Branch Hospital, Japan.
Contact Dermatitis. 1988 Feb;18(2):94-6. doi: 10.1111/j.1600-0536.1988.tb02747.x.
We patch tested 13 beauticians with hand dermatitis between 1982 and 1986. They were all young female novice beauticians or those in training. The onset of their allergic dermatitis was noticed within 1 month to 1 year of their starting this occupation. Definite positive reactions to products were seen from hair dyes (as is, open test) (6/12), cold permanent wave primary solutions (as is, open test) (7/13) and a shampoo (1% aq., closed test) (1/13). Positive reactions to allergens were seen with para-phenylenediamine (1% pet) (12/13), ammonium thioglycolate (5% aq., open test) (3/7), para-toluylenediamine (1% pet) (7/9), para-aminophenol (1% pet) (1/4), ortho-aminophenol (1% pet) (1/4), Quinoline yellow SS (0.5% pet) (1/4), nickel sulfate (2.5% pet) (1/12), cobalt sulfate (2.3% pet) (1/12), thimerosal (0.05% pet) (1/12) and procaine hydrochloride (1% pet) (1/12). Study of the prognosis showed that 5 out of 12 cases could continue their occupation, but 4 cases had persistent hand dermatitis despite protecting their hands from hair dyes with gloves, 7 cases quitted their jobs, and in 5 their hands healed while 2 cases continued to have atopic hand dermatitis. A personal or family history of atopy was frequent among the cases, so we recommend that those who have such a history should not become beauticians.
1982年至1986年间,我们对13名患有手部皮炎的美容师进行了斑贴试验。她们均为年轻的女性新手美容师或正在接受培训的人员。她们的过敏性皮炎在开始从事该职业后的1个月至1年内出现。对产品有明确阳性反应的有染发剂(原样,开放试验)(6/12)、冷烫精原液(原样,开放试验)(7/13)和一种洗发水(1%水溶液,封闭试验)(1/13)。对变应原呈阳性反应的有对苯二胺(1%凡士林)(12/13)、巯基乙酸铵(5%水溶液,开放试验)(3/7)、对甲苯二胺(1%凡士林)(7/9)、对氨基酚(1%凡士林)(1/4)、邻氨基酚(1%凡士林)(1/4)、喹啉黄SS(0.5%凡士林)(1/4)、硫酸镍(2.5%凡士林)(1/12)、硫酸钴(2.3%凡士林)(1/12)、硫柳汞(0.05%凡士林)(1/12)和盐酸普鲁卡因(1%凡士林)(1/12)。预后研究表明,12例中有5例能够继续从事该职业,但4例尽管戴手套避免接触染发剂,手部皮炎仍持续存在,7例辞职,5例手部痊愈,2例继续患有特应性手部皮炎。这些病例中个人或家族特应性病史很常见,因此我们建议有此类病史的人不应成为美容师。