van der Walle H B, Brunsveld V M
Centre of Occupational Dermatology, Ziekenhuis Rijnstate GZ, Arnhem, The Netherlands.
Contact Dermatitis. 1994 Apr;30(4):217-21. doi: 10.1111/j.1600-0536.1994.tb00647.x.
Contact dermatitis among hairdressers is common. In The Netherlands, registered sick leave for hand dermatitis among hairdressers rose from 21,050 days in 1986 to 54,293 in 1991. In a survey among 45 hairdressers in 5 different salons, 12 had a history of hand dermatitis and 16 showed moderate to severe hand dermatitis. After extensive investigations, 13 were classified as having allergic contact dermatitis and 3 cumulative irritant contact dermatitis. In the past 4 years, 103 hairdressers were extensively patch tested and glyceryl thioglycolate (GTG), ammonium persulfate and nickel sulfate were responsible for the majority of positive reactions. Hair dyes and preservatives were responsible for a moderate % of the positive reactions. Positive reactions were also found to cocamidopropyl betaine and sodium coco hydrolyzed animal protein. These 2 allergens show a rather capricious patch test reaction pattern and irritant reactions may easily be confused with allergic. The relevance of positive patch test reactions to these chemicals should always be questioned. Atopy was not a frequent cause of hand dermatitis in this study. Chemicals with a thiol group can be demonstrated with a chemical spot test. With this test, contamination of the hairdressing salon with thioglycolates was demonstrated. It is emphasized that contamination of hairdressing salons with GTG is probably a significant factor in explaining the severe flare-ups in GTG-sensitized hairdressers who no longer use GTG permanent-waving solutions.
美发师中接触性皮炎很常见。在荷兰,美发师手部皮炎的登记病假天数从1986年的21050天增至1991年的54293天。在对5家不同美发沙龙的45名美发师进行的一项调查中,12人有手部皮炎病史,16人表现出中度至重度手部皮炎。经过广泛调查,13人被归类为过敏性接触性皮炎,3人是累积性刺激性接触性皮炎。在过去4年里,对103名美发师进行了广泛的斑贴试验,巯基乙酸甘油酯(GTG)、过硫酸铵和硫酸镍是大多数阳性反应的原因。染发剂和防腐剂导致了一定比例的阳性反应。对椰油酰胺丙基甜菜碱和椰油水解动物蛋白也有阳性反应。这两种过敏原的斑贴试验反应模式相当多变,刺激性反应很容易与过敏反应混淆。斑贴试验对这些化学物质呈阳性反应的相关性始终值得质疑。在这项研究中,特应性并非手部皮炎的常见病因。含硫醇基团的化学物质可用化学点试验检测出来。通过该试验,证明了美发沙龙被巯基乙酸盐污染。需要强调的是,美发沙龙被GTG污染可能是解释不再使用GTG烫发液的GTG致敏美发师严重病情复发的一个重要因素。