Kumar Kanta, Raizada Sabrina R, Mallen Christian D, Stack Rebecca J
Faculty of Biology, Medicine and Health, School of Health Sciences, The University of Manchester, Manchester, UK.
Central Manchester University Hospitals Foundation Trust, Manchester, UK.
Patient Prefer Adherence. 2018 Apr 4;12:489-497. doi: 10.2147/PPA.S153741. eCollection 2018.
Rheumatoid arthritis (RA) causes painful joint inflammation and is incurable, but treatments control RA. Drug regimens are complex, and patients often do not take their medication as expected. Poor medication adherence can lead to poorly controlled disease and worse patient outcomes. Biologics treatments are expensive and require full engagement from patients. We have previously shown that patients from Black ethnic minority backgrounds do not fully engage into treatment plan. This study explored the patients' experiences in and satisfaction toward receiving information about biologics and future support preferences in South Asian patients with RA.
Twenty South Asian patients with RA from Royal Wolverhampton Hospitals NHS Trust and Central Manchester University Hospitals NHS Foundation Trust participated in individual semistructured interviews. Interviews were transcribed and data were analyzed by using thematic analysis approach.
Four overarching themes describe the patients' experience in and satisfaction toward receiving information on biologics: 1) current provision of information regarding the "biologics journey" and understanding of RA: in this theme, non-English-speaking patients expressed heightened anxiety about stepping up to biologics; 2) experience and perceptions of biologics: many patients were positive about the biologic experience; however, there were patient-perceived delays in getting on to the biologics; 3) factors influencing willingness to try biologics: in this theme, a number of factors were identified including seeking advice from doctors abroad; and 4) recommendations on the desired information to fully understand the use of biologics: some patients valued group discussions, while others suggested receiving RA and biologic information through a video interaction.
This novel study provides insight into South Asian RA patients' experiences in and satisfaction toward receiving information about biologics. South Asian patients with RA reported a range of perceptions about biologics and support preferences, many of which may not be shared with the non-South Asian population.
类风湿性关节炎（RA）会引发疼痛的关节炎症且无法治愈，但治疗可控制病情。药物治疗方案复杂，患者常常不按预期服药。用药依从性差会导致病情控制不佳，患者预后更差。生物制剂治疗费用高昂，需要患者全力配合。我们之前的研究表明，来自少数族裔黑人背景的患者没有充分参与治疗计划。本研究探讨了南亚类风湿性关节炎患者在获取生物制剂信息方面的经历以及满意度，以及他们对未来支持的偏好。
来自皇家伍尔弗汉普顿国民保健服务信托基金医院和曼彻斯特中心大学国民保健服务基金会信托基金医院的20名南亚类风湿性关节炎患者参与了个人半结构化访谈。访谈内容被转录，数据采用主题分析法进行分析。
四个总体主题描述了患者在获取生物制剂信息方面的经历和满意度：1）当前关于“生物制剂治疗过程”的信息提供情况以及对类风湿性关节炎的理解：在这个主题中，非英语患者对开始使用生物制剂表现出更高的焦虑；2）生物制剂的体验和认知：许多患者对生物制剂治疗体验持积极态度；然而，患者感觉在开始使用生物制剂方面存在延迟；3）影响尝试生物制剂意愿的因素：在这个主题中，确定了一些因素，包括向国外医生咨询；4）关于充分理解生物制剂使用所需信息的建议：一些患者重视小组讨论，而另一些患者建议通过视频互动获取类风湿性关节炎和生物制剂信息。
这项新研究深入了解了南亚类风湿性关节炎患者在获取生物制剂信息方面的经历和满意度。南亚类风湿性关节炎患者报告了对生物制剂的一系列认知和支持偏好，其中许多可能与非南亚人群不同。
