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人工授精中精子捐赠时对匿名的偏好:来自尼日利亚资源匮乏地区的经验

Preference for anonymity in sperm donation for artificial insemination: an experience from low-resource settings in Nigeria.

作者信息

Ezugwu Euzebus Chinonye, Eleje George U, Iyoke Chukwuemeka A, Mba Sunday G, Nnaji Henry C, Enechukwu Chukwunonso I, Nkwo Peter O

机构信息

Department of Obstetrics and Gynecology, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Ittuku Ozalla Campus, Enugu State, Nigeria.

Department of Obstetrics and Gynecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria.

出版信息

Patient Prefer Adherence. 2018 Apr 6;12:499-504. doi: 10.2147/PPA.S152868. eCollection 2018.

DOI:10.2147/PPA.S152868
PMID:29670338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5896678/
Abstract

OBJECTIVE

Anonymous sperm donation is a common practice in Nigeria with its associated legal and ethical challenges. This study aimed to investigate infertile couples' opinions about issues of sperm donor anonymity and to determine factors that might influence their preferences.

METHODS

A cross-sectional, multicentered, questionnaire-based study was conducted among infertile couples attending infertility clinics in three tertiary hospitals in the south-eastern region of Nigeria over a period of 6 months.

RESULTS

A total of 450 infertile couples were recruited consecutively from the three study centers. However, 450 females and 352 males (total=802) participated in the study. The level of awareness of artificial insemination using donor sperm for the management of male infertility among the respondents was 69.2%, while its acceptability rate was 62.7%. The majority of the respondents indicated their preference for secrecy and anonymity in sperm donation. Approximately 84% of the respondents indicated that the mode of conception should never be disclosed to the donor-conceived child, and ~92% of them indicated that the identity of the sperm donor should never be revealed to the donor-conceived child. Fear of adverse effect of such disclosure on the child and the possible of rejection of the father in order to seek for the donor were the major reasons for their preference for anonymity.

CONCLUSION

Although it has been argued that every child has a right to know their genetic parents, the reasons proffered by the respondents for their preference for anonymity cannot be totally ignored. Establishing a regulatory body and enacting laws that will address both the ethical and legal issues associated with gamete donation in the developing world will go a long way in promoting openness and honest communication with donor-conceived children.

摘要

目的

匿名捐精在尼日利亚是一种常见做法,存在相关的法律和伦理挑战。本研究旨在调查不孕夫妇对精子捐献者匿名问题的看法,并确定可能影响其偏好的因素。

方法

在尼日利亚东南部地区的三家三级医院的不孕不育诊所,对前来就诊的不孕夫妇进行了为期6个月的横断面、多中心、基于问卷的研究。

结果

从三个研究中心连续招募了450对不孕夫妇。然而,450名女性和352名男性(共802人)参与了研究。受访者中使用供体精子人工授精治疗男性不育的知晓率为69.2%,接受率为62.7%。大多数受访者表示他们倾向于精子捐献的保密性和匿名性。约84%的受访者表示受孕方式永远不应告知通过捐献精子受孕的孩子,约92%的受访者表示精子捐献者的身份永远不应透露给通过捐献精子受孕的孩子。担心这种披露对孩子产生不利影响以及孩子可能为寻找捐献者而拒绝父亲是他们倾向于匿名的主要原因。

结论

尽管有人认为每个孩子都有权知道自己的基因父母,但受访者倾向于匿名的理由不能完全被忽视。在发展中国家建立一个监管机构并制定相关法律,以解决与配子捐赠相关的伦理和法律问题,将大大有助于促进与通过捐献精子受孕的孩子进行开放和诚实的沟通。

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本文引用的文献

1
The end of donor anonymity: how genetic testing is likely to drive anonymous gamete donation out of business.捐赠者匿名制的终结:基因检测如何可能使匿名配子捐赠不再可行。
Hum Reprod. 2016 Jun;31(6):1135-40. doi: 10.1093/humrep/dew065. Epub 2016 Apr 12.
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A unique view on male infertility around the globe.对全球男性不育症的独特见解。
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Int J Womens Health. 2014 Feb 12;6:201-5. doi: 10.2147/IJWH.S56324. eCollection 2014.
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How to kill gamete donation: retrospective legislation and donor anonymity.如何扼杀配子捐赠:回顾性立法与供者匿名。
Hum Reprod. 2012 Oct;27(10):2881-5. doi: 10.1093/humrep/des218. Epub 2012 Jul 10.
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Psycho-social, ethical and legal arguments for and against the retrospective release of information about donors to donor-conceived individuals in Australia.关于在澳大利亚支持和反对向通过捐赠受孕出生的个人追溯披露捐赠者信息的社会心理、伦理和法律论据。
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