Faculty of Science, Chemistry Department, MSKU, 48000 Kotekli, Mugla, Turkey.
Faculty of Science, Biochemistry Department, Ege University, 35100 Bornova, Izmir, Turkey.
Mikrochim Acta. 2019 Feb 20;186(3):196. doi: 10.1007/s00604-019-3321-0.
Metal-organic frameworks (MOFs) are porous coordination polymers (CP) produced by metal-based nodes and multitopic organic ligands. Based on their porous and microcrystalline powder structures, they have initially been used for storage, catalysis and separation. Then, because of their advantageous properties like ease of the tailoring, they also have been applied in areas like chemical sensing, biological applications, etc. The CPs were combined with molecules such as organic dyes, small biomolecules, nanomaterials like nanoparticles, nanowires, nanofibers and polymers and as a result, composite MOFs have been produced. By this way, better mechanical stability, conductivity, and catalytic performance were obtained. This review (with 135 refs.) summarizes the progress made in the past years in the field of electrochemical and optical sensing based on the use of MOFs. Following an introduction into the field, large sections cover MOF based sensors exploiting (a) carbon nanomaterials (with subsections on carbon nanotubes, graphene and its derivatives), (b) metal/metal oxide MOFs; including gold, silver, copper and/or copper oxide nanoparticle and other metal/MOF composites. Enzyme mimicking MOFs are discussed next. In this context, after the brief information about focused MOFs, the nanomaterial/MOF composites were discussed and related examples were presented. Graphical abstract MOF structures in Sensing Systems.
金属-有机骨架（MOFs）是由基于金属的节点和多齿有机配体组成的多孔配位聚合物（CP）。基于其多孔和微晶粉末结构，它们最初被用于存储、催化和分离。然后，由于它们易于修饰等有利特性，它们也被应用于化学传感、生物应用等领域。CP 与有机染料、小分子生物分子、纳米材料（如纳米粒子、纳米线、纳米纤维和聚合物）结合，从而产生了复合 MOFs。通过这种方式，获得了更好的机械稳定性、导电性和催化性能。这篇综述（引用了 135 篇参考文献）总结了过去几年在基于 MOFs 的电化学和光学传感领域取得的进展。在介绍该领域之后，大部分内容涵盖了基于（a）碳纳米材料（包括碳纳米管、石墨烯及其衍生物）和（b）金属/金属氧化物 MOFs 的 MOF 传感器，包括金、银、铜和/或氧化铜纳米粒子和其他金属/ MOF 复合材料。接下来讨论了酶模拟 MOFs。在这方面，在简要介绍了重点 MOFs 之后，讨论了纳米材料/ MOF 复合材料，并介绍了相关示例。
