Nanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Nanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Talanta. 2018 Jul 1;184:537-556. doi: 10.1016/j.talanta.2018.02.088. Epub 2018 Feb 26.
Recent advances in nanotechnology are as a result of the development of engineered nanoparticles. Efficiently, metallic nanoparticles have been widely exploited for biomedical application and among them, gold nanoparticles (AuNPs) are highly remarkable. Consequent upon their significant nature, spherical and gold nanorods (Au NRs) nanoparticles attract extreme attention. Their intrinsic features such as optical, electronic, physicochemical and, surface plasmon resonance (SPR); which can be altered by changing the characterizations of particles such as shape, size, aspect ratio, or environment; ease of synthesis and functionalization properties have resulted to various applications in different fields of biomedicine such as sensing, targeted drug delivery, imaging, photothermal and photodynamic therapy as well as the modulation of two or three applications. This article reviewed the popular AuNPs synthesis methods and mentioned their established applications in various demands, especially in biological sensing.
纳米技术的最新进展是工程纳米粒子发展的结果。高效地，金属纳米粒子已被广泛用于生物医学应用，其中金纳米粒子（AuNPs）非常显著。由于其重要性质，球形和金纳米棒（AuNRs）纳米粒子引起了极大的关注。它们的固有特性，如光学、电子、物理化学和表面等离子体共振（SPR），可以通过改变粒子的特性来改变，如形状、大小、纵横比或环境；易于合成和功能化特性导致了在不同领域的生物医学中的各种应用，如传感、靶向药物输送、成像、光热和光动力治疗以及两种或三种应用的调节。本文综述了流行的 AuNPs 合成方法，并提到了它们在各种需求中的已建立的应用，特别是在生物传感中。
