Ramalingam Vaikundamoorthy
Department of Animal Science, Chonbuk National University, Jeonju, Republic of Korea.
Adv Colloid Interface Sci. 2019 Sep;271:101989. doi: 10.1016/j.cis.2019.101989. Epub 2019 Jul 12.
In a couple of decades, nanotechnology has become a trending area in science due to it covers all subject that combines diverse range of fields including but not limited to chemistry, physics and medicine. Various metal and metal oxide nanomaterials have been developed for wide range applications. However, the application of gold nanostructures and nanoparticles has been received more attention in various biomedical applications. The unique property of gold nanoparticles (AuNPs) is surface plasmon resonance (SPR) that determine the size, shape and stability. The wide surface area of AuNPs eases the proteins, peptides, oligonucleotides, and many other compounds to tether and enhance the biological activity of AuNPs. AuNPs have multifunctionality including antimicrobial, anticancer, drug and gene delivery, sensing applications and imaging. This state-of-the-art review is focused on the role of unique properties of AuNPs in multifunctionality and its various applications.
在几十年的时间里,纳米技术因其涵盖了所有结合了包括但不限于化学、物理和医学等多种领域的学科,已成为科学界的一个热门领域。各种金属和金属氧化物纳米材料已被开发用于广泛的应用。然而,金纳米结构和纳米颗粒在各种生物医学应用中受到了更多关注。金纳米颗粒(AuNPs)的独特性质是表面等离子体共振(SPR),它决定了尺寸、形状和稳定性。AuNPs的大表面积便于蛋白质、肽、寡核苷酸和许多其他化合物附着,并增强AuNPs的生物活性。AuNPs具有多种功能,包括抗菌、抗癌、药物和基因递送、传感应用以及成像。这篇最新综述聚焦于AuNPs独特性质在多功能性及其各种应用中的作用。