利用可见和近红外光学相干断层扫描技术量化光学特性以可视化食管微波消融区域。
Quantifying optical properties with visible and near-infrared optical coherence tomography to visualize esophageal microwave ablation zones.
作者信息
Niemeier Ryan C, Etoz Sevde, Gil Daniel A, Skala Melissa C, Brace Christopher L, Rogers Jeremy D
机构信息
Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Morgridge Institute for Research, University of Wisconsin-Madison, Madison, WI 53706, USA.
出版信息
Biomed Opt Express. 2018 Mar 13;9(4):1648-1663. doi: 10.1364/BOE.9.001648. eCollection 2018 Apr 1.
Microwave ablation is a minimally invasive image guided thermal therapy for cancer that can be adapted to endoscope use in the gastrointestinal (GI) tract. Microwave ablation in the GI tract requires precise control over the ablation zone that could be guided by high resolution imaging with quantitative contrast. Optical coherence tomography (OCT) provides ideal imaging resolution and allows for the quantification of tissue scattering properties to characterize ablated tissue. Visible and near-infrared OCT image analysis demonstrated increased scattering coefficients ( ) in ablated versus normal tissues (Vis: 347.8%, NIR: 415.0%) and shows the potential for both wavelength ranges to provide quantitative contrast. These data suggest OCT could provide quantitative image guidance and valuable information about antenna performance .
微波消融是一种用于癌症的微创图像引导热疗法，可适用于胃肠道的内窥镜使用。胃肠道中的微波消融需要精确控制消融区域，这可以通过具有定量对比的高分辨率成像来引导。光学相干断层扫描（OCT）提供了理想的成像分辨率，并允许对组织散射特性进行量化，以表征消融组织。可见和近红外OCT图像分析表明，与正常组织相比，消融组织中的散射系数增加（可见光：347.8%，近红外：415.0%），并且显示了两个波长范围都有提供定量对比的潜力。这些数据表明，OCT可以提供定量图像引导以及有关天线性能的有价值信息。
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