Baumgart Mariusz, Wiśniewski Marcin, Grzonkowska Magdalena, Badura Mateusz, Biernacki Maciej, Siedlecki Zygmunt, Szpinda Aleksandra, Szpinda Michał, Pawlak-Osińska Katarzyna
Department of Normal Anatomy, The Ludwik Rydygier Collegium Medicum in Bydgoszcz, The Nicolaus Copernicus University in Toruń, Łukasiewicza 1 Street, 85-821, Bydgoszcz, Poland.
Department of Neurosurgery, Neurotraumatology and Pediatric Neurosurgery, The Ludwik Rydygier Collegium Medicum in Bydgoszcz, The Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Surg Radiol Anat. 2018 Sep;40(9):1047-1054. doi: 10.1007/s00276-018-2018-0. Epub 2018 Apr 19.
An understanding of the development of the ilium's primary ossification center may be useful in both determining the fetal stage and maturity, and for detecting congenital disorders. This study was performed to quantitatively examine the ilium's primary ossification center with respect to its linear, planar and volumetric parameters.
Using methods of CT, digital-image analysis and statistics, the size of the ilium's primary ossification center in 42 spontaneously aborted human fetuses of crown-rump length (CRL) ranged from 130 to 265 mm (aged 18-30 weeks) was studied.
With no sex and laterality differences, the best fit growth dynamics for the ilium's primary ossification center was modelled by the following functions: y = - 63.138 + 33.413 × ln(CRL) ± 1.609 for its vertical diameter, y = - 59.220 + 31.353 × ln(CRL) ± 1.736 for its transverse diameter, y = - 105.681 + 1.137 × CRL ± 16.035 for its projection surface area, and y = 478.588 + 4.035 × CRL ± 14.332 for its volume. The shape of the ilium's primary ossification center did not change over the study period, because its transverse -to- vertical diameter ratio was stable at the level of 0.94 ± 0.07. Conclusions The size of the ilium's primary ossification center displays neither sex nor laterality differences. The ilium's primary ossification center grows logarithmically with respect to its vertical and transverse diameters, and linearly with respect to its projection surface area and volume. The shape of the ilium's primary ossification center does not change throughout the examined period. The obtained quantitative data of the ilium's primary ossification center is considered normative for respective prenatal weeks and may contribute to the prenatal ultrasound diagnostics of congenital defects.
了解髂骨初级骨化中心的发育情况，对于确定胎儿阶段和成熟度以及检测先天性疾病可能是有用的。本研究旨在对髂骨初级骨化中心的线性、平面和体积参数进行定量研究。
采用CT、数字图像分析和统计学方法，研究了42例自然流产的人类胎儿（冠臀长[CRL]范围为130至265mm，年龄为18至30周）髂骨初级骨化中心的大小。
在无性别和左右侧差异的情况下，髂骨初级骨化中心的最佳拟合生长动力学由以下函数模拟：垂直直径为y = -63.138 + 33.413×ln(CRL)±1.609，横径为y = -59.220 + 31.353×ln(CRL)±1.736，投影表面积为y = -105.681 + 1.137×CRL±16.035，体积为y = 478.588 + 4.035×CRL±14.332。在研究期间，髂骨初级骨化中心的形状没有变化，因为其横径与垂直直径之比稳定在0.94±0.07的水平。结论髂骨初级骨化中心的大小不存在性别和左右侧差异。髂骨初级骨化中心的垂直和横径呈对数生长，投影表面积和体积呈线性生长。在整个检查期间，髂骨初级骨化中心的形状没有变化。所获得的髂骨初级骨化中心的定量数据被认为是各产前周的标准数据，可能有助于先天性缺陷的产前超声诊断。
