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瑞士年轻人麻疹疫苗接种率显著提高:是宣传活动还是队列效应?

Marked increase in measles vaccination coverage among young adults in Switzerland: a campaign or cohort effect?

机构信息

Division of Communicable Diseases, Federal Office of Public Health, Berne, Switzerland.

出版信息

Int J Public Health. 2018 Jun;63(5):589-599. doi: 10.1007/s00038-018-1102-x. Epub 2018 Apr 19.

Abstract

OBJECTIVES

To evaluate the impact of the Swiss measles elimination strategy-including a mass media campaign-on vaccination coverage and awareness among young adults aged 20-29 years.

METHODS

Comparison of the results of two cross-sectional population surveys in 2012 and 2015.

RESULTS

Documented vaccination coverage increased from 77 to 88% for two doses of measles vaccine. Major determinants of complete vaccination were survey year, birth cohort, sex and the absence of prior measles disease. If birth cohort and prior history of measles disease are included as factors in a multivariate model, the difference between 2012 and 2015 vanishes.

CONCLUSIONS

The marked increase in complete measles vaccination coverage is due to a cohort effect, owing to the introduction of the second dose of vaccine in 1996. Most of the vaccinations were administered before the national strategy was implemented and vaccination catch-ups did not increase during the campaign in young adults. Nevertheless, this study provides evidence of an improvement in the awareness of measles and measles vaccination in young adults, which may result in an impact on measles vaccination coverage in the near future.

摘要

目的

评估瑞士麻疹消除策略(包括大众媒体宣传活动)对 20-29 岁年轻成年人疫苗接种覆盖率和意识的影响。

方法

比较 2012 年和 2015 年两次横断面人群调查的结果。

结果

记录的两剂麻疹疫苗接种覆盖率从 77%增加到 88%。完全接种的主要决定因素是调查年份、出生队列、性别以及是否有先前的麻疹疾病史。如果将出生队列和先前的麻疹病史作为多变量模型中的因素,则 2012 年和 2015 年之间的差异消失。

结论

完全麻疹疫苗接种覆盖率的显著增加是由于队列效应,这是由于 1996 年引入了第二剂疫苗。大多数疫苗接种是在国家战略实施之前进行的,并且在年轻人的宣传活动中没有增加疫苗接种覆盖率。尽管如此,这项研究提供了证据,证明了年轻人对麻疹和麻疹疫苗接种的认识有所提高,这可能会在不久的将来对麻疹疫苗接种覆盖率产生影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27db/5976707/61930a46bd3a/38_2018_1102_Fig1_HTML.jpg

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