Regenerative Medicine and Disability Research (RMDR) Lab, Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL,, 61007, USA.
Curr Osteoporos Rep. 2018 Jun;16(3):236-245. doi: 10.1007/s11914-018-0441-0.
Recently, significant progress has been made in the research related to regenerative medicine. At the same time, biomedical implants in orthopedics and dentistry are facing many challenges and posing clinical concerns. The purpose of this chapter is to provide an overview of the clinical applications of current regenerative strategies to the fields of dentistry and orthopedic surgery. The main research question in this review is: What are the major advancement strategies in regenerative medicine that can be used for implant research?
The implant surfaces can be modified through patient-specific stem cells and plasma coatings, which may provide methods to improve osseointegration and sustainability of the implant. Overall understanding from the review suggesting that the outcome from the studies could lead to identify optimum solutions for many concerns in biomedical implants and even in drug developments as a long-term solution to orthopedic and dental patients.
目的综述：最近，再生医学的相关研究取得了重大进展。与此同时，骨科和牙科的生物医学植入物也面临着诸多挑战和临床问题。本章旨在概述当前再生策略在牙科和骨科领域的临床应用。本篇综述的主要研究问题是：有哪些主要的再生医学进展策略可用于植入物研究？
发现：可以通过患者特异性干细胞和等离子体涂层来修饰植入物表面，这可能为改善植入物的骨整合和可持续性提供方法。综述表明，这些研究的结果可能为生物医学植入物的许多问题找到最佳解决方案，甚至为长期解决骨科和牙科患者的问题提供药物开发的最佳解决方案。
