Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA, USA.
Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Clin Psychol Rev. 2019 Apr;69:83-96. doi: 10.1016/j.cpr.2018.04.002. Epub 2018 Apr 11.
There is a tremendous global and national (US) burden associated with alcohol misuse and alcohol use disorder (AUD). Further, of the mental health disorders, AUD has the widest treatment gap. Thus, there is a critical need for improved understanding of the etiology, maintenance, and treatment of AUD. The application of cognitive science to the study of AUD has a longstanding history of attempting to meet this need. In this selective review, we identified and focused on four domains of recent (i.e., in the last decade) applications of cognitive science to the study of AUD: implicit cognitive biases, executive function, behavioral economic approaches to alcohol decision making, and functional connectivity neuroimaging. We highlighted advances within these four domains and considered them in the context of dual process models of addiction, which focus on the contribution and interplay of two complementary neurocognitive systems (impulsive and control systems). Findings across the domains were generally consistent with dual process models. They also suggest the need for further model refinements, including integrating behavioral economic approaches and findings from functional connectivity neuroimaging studies. Research evaluating candidate interventions associated with these domains is emergent but promising, suggesting important directions for future research.
酗酒和酒精使用障碍(AUD)与巨大的全球和国家(美国)负担有关。此外,在精神健康障碍中,AUD 的治疗缺口最大。因此,迫切需要更好地了解 AUD 的病因、维持和治疗。认知科学在 AUD 研究中的应用有着悠久的历史,试图满足这一需求。在本次选择性回顾中,我们确定并关注了认知科学在 AUD 研究中的四个最近(即过去十年)应用领域:内隐认知偏差、执行功能、酒精决策的行为经济学方法以及功能连接神经影像学。我们强调了这四个领域的进展,并在成瘾的双重过程模型的背景下对其进行了考虑,该模型侧重于两个互补的神经认知系统(冲动系统和控制系统)的贡献和相互作用。各领域的研究结果通常与双重过程模型一致。它们还表明需要进一步完善模型,包括整合行为经济学方法和功能连接神经影像学研究的结果。评估与这些领域相关的候选干预措施的研究正在出现,但很有希望,为未来的研究指明了重要方向。