Gonçalves Mariana, Moreira Sónia, Gaspar Elsa, Santos Lèlita
Department of Internal Medicine, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
BMJ Case Rep. 2018 Apr 21;2018:bcr-2018-224315. doi: 10.1136/bcr-2018-224315.
Q fever is a zoonotic disease caused by that usually presents with non-specific or benign constitutional symptoms. Diagnosis is often challenging and, after acute Q fever, 1%-5% of patients can develop chronic disease. We present an 80-year-old male patient who was admitted due to a 3 months history of fever, productive cough, myalgia, weight loss, headache and hearing loss. Chronic Q fever was confirmed by positive antiphase I immunoglobulin G. Frequent locations of chronic infection was discarded, and ear CT revealed a right mastoid infection. He was treated with doxycycline and hydroxychloroquine for 18 months with significant improvement. This is a rare case of chronic Q fever presenting with otomastoiditis that has never been described.
Q热是一种由[病原体未提及]引起的人畜共患病,通常表现为非特异性或良性全身症状。诊断往往具有挑战性,急性Q热后,1% - 5%的患者会发展为慢性病。我们报告一名80岁男性患者,因发热、咳痰、肌痛、体重减轻、头痛和听力丧失3个月病史入院。抗I相免疫球蛋白G阳性确诊为慢性Q热。排除慢性感染的常见部位,耳部CT显示右乳突感染。他接受多西环素和羟氯喹治疗18个月,病情显著改善。这是一例罕见的以耳乳突炎为表现的慢性Q热病例,此前从未有过描述。