Javia Ankit, Amrutiya Jitendra, Lalani Rohan, Patel Vivek, Bhatt Priyanka, Misra Ambikanandan
Faculty of Pharmacy, Kalabhavan Campus, The Maharaja Sayajirao University of Baroda, Vadodara 390001 Gujarat, India.
Ther Deliv. 2018 May;9(5):375-386. doi: 10.4155/tde-2017-0061.
The management of wounds and burns is becoming difficult using conventional therapeutics available due to resistance development by microbes. Therefore, there is an utmost need to develop therapeutic alternatives to these agents. Antimicrobial peptides have emerged as a novel class of agents for the effective management of wounds and burns due to their potent nature along with minimal chances of resistance development against them. This article focuses on highlighting the importance of these antimicrobial peptides among the various therapeutic alternatives for burns and wounds. Further, effective delivery strategies for these agents that are being employed and investigated are reported along with an overview of the importance of these agents in the coming years.
由于微生物产生耐药性，使用现有的传统疗法来处理伤口和烧伤正变得困难。因此，迫切需要开发这些药物的替代疗法。抗菌肽已成为一类新型药物，因其强大的特性以及对其产生耐药性的可能性极小，可有效处理伤口和烧伤。本文着重强调这些抗菌肽在烧伤和伤口的各种治疗替代方案中的重要性。此外，还报告了正在采用和研究的这些药物的有效递送策略，并概述了这些药物在未来几年的重要性。
