Martinelli José Eduardo, Cecato Juliana Francisca, Martinelli Marcos Oliveira, de Melo Brian Alvarez Ribeiro, Aprahamian Ivan
MS, PhD, Division of Geriatrics and Gerontology, Department of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, SP, Brazil.
MD, Division of Geriatrics and Gerontology, Department of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, SP, Brazil.
Dement Neuropsychol. 2018 Jan-Mar;12(1):54-60. doi: 10.1590/1980-57642018dn12-010008.
The Pentagon Drawing Test (PDT) is a common cognitive screening test.
The aim of this study was to evaluate performance properties of a specific PDT scoring scale in older adults with Alzheimer's disease (AD) and healthy controls.
A cross-sectional study of 390 elderly patients, aged 60 years or older with at least two years of education was conducted. All participants completed clinical and neuropsychological evaluations, including the Cambridge Cognitive Examination, the Mini-Mental State Examination (MMSE), and the Clock Drawing Test. All PDT were blindly scored with the scale of Bourke et al.
PDT analyses of the binary score on the MMSE (0 or 1 point) did not discriminate AD from controls (p = 0.839). However, when PDT was analyzed using the Bourke et al. scale, the two groups could be distinguished (p <0.001). PDT was not affected by education, showed sensitivity of 85.5% and specificity of 66.9%, discriminated different clinical stages of dementia, and correlated with the other cognitive tests (p <0.001). A 1-point difference on the Bourke et al. scale was associated with an odds ratio of 3.46 for AD.
PDT can be used as a cognitive screen for suspected cases of dementia, especially AD, irrespective of educational level.
五角形绘图测试(PDT)是一种常见的认知筛查测试。
本研究的目的是评估一种特定的PDT评分量表在患有阿尔茨海默病(AD)的老年人和健康对照中的性能特征。
对390名60岁及以上、至少接受过两年教育的老年患者进行了一项横断面研究。所有参与者均完成了临床和神经心理学评估,包括剑桥认知检查、简易精神状态检查(MMSE)和时钟绘图测试。所有PDT均采用伯克等人的量表进行盲法评分。
对MMSE二元评分(0或1分)的PDT分析未能区分AD患者和对照组(p = 0.839)。然而,当使用伯克等人的量表对PDT进行分析时,两组可以区分开来(p <0.001)。PDT不受教育程度的影响,敏感性为85.5%,特异性为66.9%,可区分痴呆的不同临床阶段,并与其他认知测试相关(p <0.001)。伯克等人的量表上1分的差异与AD的优势比3.46相关。
PDT可作为疑似痴呆病例,尤其是AD的认知筛查工具,而不论教育程度如何。