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小儿肠套叠复发的危险因素:一项回顾性研究。

Risk factors for recurrence of intussusception in pediatric patients: A retrospective study.

作者信息

Xie Xiaolong, Wu Yang, Wang Qi, Zhao Yiyang, Xiang Bo

机构信息

Department of pediatric surgery, West China hospital, Sichuan University, China.

出版信息

J Pediatr Surg. 2018 Nov;53(11):2307-2311. doi: 10.1016/j.jpedsurg.2018.03.023. Epub 2018 Mar 28.

DOI:10.1016/j.jpedsurg.2018.03.023
PMID:29685487
Abstract

OBJECTIVES

The aim of this study was to explore the risk factors associated with recurrence of intussusception after operative or nonoperative reduction in children.

METHODS

Between January 2004 and December 2012, patients with intussusception treated with nonoperative and operative reduction were retrospectively analyzed. We included the patients who were diagnosed with intussusception from the age of 0 year to 18 years who received nonoperative and operative reduction as an initial treatment. The data collected included demographic data (sex, age, and bodyweight), symptoms (vomiting, abdominal pain, rectal bleeding, diarrhea, distention, constipation, and duration of symptoms), signs (temperature, palpable mass, and location of the mass), investigations (ultrasound findings) and the method of reduction.

RESULTS

The risk factors for recurrence of idiopathic intussusception were analyzed by the univariable analysis and multivariable analysis. In the univariable model, the significant risk factors for recurrence of intussusception analyzed were age, bodyweight, duration of symptoms, rectal bleeding, poor prognosis signs on ultrasound scans, location of mass, and pathological lead point. After multivariable analysis was done, we found that the significant risk factors for recurrence of intussusception were age ≥ 2 years (OR = 5.597, P = 0.044), duration of symptoms ≥48 h (OR = 91.664, P < 0.001), rectal bleeding (OR = 4.758, P = 0.009), location of mass (left over right side) (OR = 0.038, P < 0.001), pathological lead point (OR = 0.002, P < 0.001).

CONCLUSION

Our study found that age ≥ 2 years, duration of symptoms≥48 h, rectal bleeding, location of mass (left over right side) and pathological lead point were risk factors for recurrence of intussusception.

LEVEL OF EVIDENCE

Prognosis study.

TYPE OF STUDY

Retrospective study.

摘要

目的

本研究旨在探讨儿童肠套叠手术复位或非手术复位后复发的相关危险因素。

方法

回顾性分析2004年1月至2012年12月期间接受非手术和手术复位治疗的肠套叠患者。纳入年龄在0岁至18岁之间、以非手术和手术复位作为初始治疗的肠套叠确诊患者。收集的数据包括人口统计学数据(性别、年龄和体重)、症状(呕吐、腹痛、直肠出血、腹泻、腹胀、便秘及症状持续时间)、体征(体温、可触及肿块及肿块位置)、检查(超声检查结果)以及复位方法。

结果

通过单因素分析和多因素分析对特发性肠套叠复发的危险因素进行分析。在单因素模型中,分析得出的肠套叠复发的显著危险因素为年龄、体重、症状持续时间、直肠出血、超声检查预后不良体征、肿块位置及病理性引导点。多因素分析后发现,肠套叠复发的显著危险因素为年龄≥2岁(OR = 5.597,P = 0.044)、症状持续时间≥48小时(OR = 91.664,P < 0.001)、直肠出血(OR = 4.758,P = 0.009)、肿块位置(左侧多于右侧)(OR = 0.038,P < 0.001)、病理性引导点(OR = 0.002,P < 0.001)。

结论

我们的研究发现年龄≥2岁、症状持续时间≥48小时、直肠出血、肿块位置(左侧多于右侧)及病理性引导点是肠套叠复发的危险因素。

证据水平

预后研究。

研究类型

回顾性研究。

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