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[新型冠状病毒肺炎对小儿肠套叠的影响:韩国单中心10年经验的回顾性研究]

[The Effect of COVID-19 on Pediatric Intussusception: A Retrospective Study of a Single Center in South Korea with 10-Year Experience].

作者信息

Yoo Yeo Jin, Je Bo-Kyung, Choi Ga Young, Lee Jee Hyun, Choi Sunkyu, Lee Ji Young

出版信息

Taehan Yongsang Uihakhoe Chi. 2022 Mar;83(2):304-316. doi: 10.3348/jksr.2021.0089. Epub 2022 Feb 25.

DOI:10.3348/jksr.2021.0089
PMID:36237933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9514438/
Abstract

PURPOSE

To evaluate the effect of the emergence of coronavirus disease-19 (COVID-19) on pediatric intussusception.

MATERIALS AND METHODS

Patients (< 18 years) who were diagnosed with intussusception and received enema reduction from 2011 to 2020 were included. We reviewed the demographics, yearly/monthly/seasonal incidence of intussusception, method and failure rate of enema reduction, recurrence rate of intussusception, surgical record, and pathologic report. Subsequently, we investigated the differences in mean age, failure rate of enema reduction, and recurrence rate of intussusception between the cases in 2020 and those in the period from 2011 to 2019.

RESULTS

A total of 859 enema reductions were performed during the past decade, more in males and in the age < 1 year (mean age, 22.2 months). The yearly incidence was highest in 2014 and lowest in 2020, and the monthly incidence was highest on December and September. The cases in 2020 ( = 27) had a lower mean age (18.1 months vs. 22.8 months), higher failure rate of enema reduction (7.4% vs. 2.4%), and higher recurrence rate of intussusception (14.8% vs 7.3%) compared with those that occurred between 2011 and 2019 ( = 832). However, these results did not show statistical significance ( = 0.07, = 0.15, = 0.14, respectively).

CONCLUSION

With the emergence of COVID-19, the number of enema reductions was remarkably decreased with a lower mean age, higher failure rate, and higher recurrence rate.

摘要

目的

评估新型冠状病毒肺炎(COVID-19)的出现对小儿肠套叠的影响。

材料与方法

纳入2011年至2020年期间诊断为肠套叠并接受灌肠复位治疗的18岁以下患者。我们回顾了人口统计学资料、肠套叠的年/月/季节发病率、灌肠复位的方法和失败率、肠套叠的复发率、手术记录和病理报告。随后,我们调查了2020年病例与2011年至2019年期间病例在平均年龄、灌肠复位失败率和肠套叠复发率方面的差异。

结果

在过去十年中,共进行了859次灌肠复位,男性及1岁以下(平均年龄22.2个月)患者接受灌肠复位的次数更多。年发病率在2014年最高,2020年最低,月发病率在12月和9月最高。与2011年至2019年发生的病例(n = 832)相比,2020年的病例(n = 27)平均年龄较低(18.1个月对22.8个月),灌肠复位失败率较高(7.4%对2.4%),肠套叠复发率较高(14.8%对7.3%)。然而,这些结果未显示出统计学意义(P值分别为0.07、0.15、0.14)。

结论

随着COVID-19的出现,灌肠复位的次数显著减少,平均年龄降低,失败率和复发率升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/facead773a88/jksr-83-304-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/65557023c376/jksr-83-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/967c8859edac/jksr-83-304-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/facead773a88/jksr-83-304-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/65557023c376/jksr-83-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/967c8859edac/jksr-83-304-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ae/9514438/facead773a88/jksr-83-304-g003.jpg

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Epidemiol Health. 2020;42:e2020064. doi: 10.4178/epih.e2020064. Epub 2020 Sep 7.
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Nationwide Population-Based Epidemiologic Study on Childhood Intussusception in South Korea: Emphasis on Treatment and Outcomes.
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Pediatr Gastroenterol Hepatol Nutr. 2020 Jul;23(4):329-345. doi: 10.5223/pghn.2020.23.4.329. Epub 2020 Jul 3.
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Abdominal lymph node size in children at computed tomography.儿童计算机断层扫描中的腹部淋巴结大小。
Pediatr Radiol. 2020 Aug;50(9):1263-1270. doi: 10.1007/s00247-020-04715-z. Epub 2020 Jun 7.
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Air contrast enema reduction of single and recurrent ileocolic intussusceptions in children: patterns, management and outcomes.空气对比灌肠在儿童单发和复发性回肠-结肠肠套叠中的应用:模式、处理和结果。
Pediatr Radiol. 2020 May;50(5):664-672. doi: 10.1007/s00247-020-04612-5. Epub 2020 Jan 31.
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Characteristics of intussusception among children in Korea: a nationwide epidemiological study.韩国儿童肠套叠的特征:一项全国性的流行病学研究。
BMC Pediatr. 2019 Jun 28;19(1):211. doi: 10.1186/s12887-019-1592-6.
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