Department of Medicine and Health Sciences "V. Tiberio", University of Molise, Via de Sanctis s.n.c, 86100 Campobasso, Italy.
FB Dermatology, Borupvang 5C, 2750 Ballerup, Denmark.
Nutrients. 2018 Apr 22;10(4):522. doi: 10.3390/nu10040522.
Astaxanthin, a xanthophyll carotenoid, is a secondary metabolite naturally synthesized by a number of bacteria, microalgae, and yeasts. The commercial production of this pigment has traditionally been performed by chemical synthesis, but the microalga appears to be the most promising source for its industrial biological production. Due to its collective diverse functions in skin biology, there is mounting evidence that astaxanthin possesses various health benefits and important nutraceutical applications in the field of dermatology. Although still debated, a range of potential mechanisms through which astaxanthin might exert its benefits on skin homeostasis have been proposed, including photoprotective, antioxidant, and anti-inflammatory effects. This review summarizes the available data on the functional role of astaxanthin in skin physiology, outlines potential mechanisms involved in the response to astaxanthin, and highlights the potential clinical implications associated with its consumption.
虾青素是一种叶黄素类胡萝卜素，是许多细菌、微藻和酵母自然合成的次级代谢产物。这种色素的商业生产传统上是通过化学合成来完成的，但微藻似乎是其工业生物生产最有前途的来源。由于虾青素在皮肤生物学中具有多种功能，越来越多的证据表明，虾青素在皮肤科领域具有多种健康益处和重要的营养应用。尽管仍有争议，但已经提出了一系列虾青素可能对皮肤内稳态发挥作用的潜在机制，包括光保护、抗氧化和抗炎作用。本综述总结了虾青素在皮肤生理学中的功能作用的现有数据，概述了虾青素作用的潜在机制，并强调了其消费相关的潜在临床意义。
