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Association between Ambient Air Pollution and Asthma Prevalence in Different Population Groups Residing in Eastern Texas, USA.美国得克萨斯州东部不同人群中环境空气污染与哮喘患病率之间的关联。
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Association between Air Pollutants and Asthma Emergency Room Visits and Hospital Admissions in Time Series Studies: A Systematic Review and Meta-Analysis.时间序列研究中空气污染物与哮喘急诊就诊及住院之间的关联：一项系统评价与荟萃分析
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Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review.室外空气污染会引发新的哮喘病例吗？生物学上的可能性和证据；综述。
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空气污染对中国东北地区成人哮喘住院的影响。

Influence of Air Pollution on Hospital Admissions in Adult Asthma in Northeast China.

机构信息

Department of Respiratory Medicine, The First Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, China.

Department of Vascular Surgery, The First Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, China.

出版信息

Chin Med J (Engl). 2018 May 5;131(9):1030-1033. doi: 10.4103/0366-6999.230735.

DOI:10.4103/0366-6999.230735
PMID:29692372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5937309/
Abstract

BACKGROUND

Asthma is a common chronic respiratory disease and is related to air pollution exposure. However, only a few studies have concentrated on the association between air pollution and adult asthma. Moreover, the results of these studies are controversial. Therefore, the present study aimed to analyze the influence of various pollutants on hospitalization due to asthma in adults.

METHODS

A total of 1019 unrelated hospitalized adult asthma patients from Northeast China were recruited from 2014 to 2016. Daily average concentrations of air pollutants (particulate matter <2.5 μm [PM], particulate matter <10 μm [PM], sulfur dioxide [SO], nitrogen dioxide [NO], and carbon monoxide [CO]) were obtained from the China National Environmental Monitoring Centre website from 2014 to 2016. Cox logistic regression analysis was used to analyze the relationship between air pollutants and hospital admissions in adult asthma.

RESULTS

The maximum odds ratio (OR) value for most air pollutants occurred on lag day 1. Lag day 1 was chosen as the exposure period, and 8 days before onset was chosen as the control period. Three pollutants (PM, CO, and SO) were entered into the regression equation, and the corresponding OR (95% confidence interval) was 0.995 (0.991-0.999), 3.107 (1.607-6.010), and 0.979 (0.968-0.990), respectively.

CONCLUSIONS

A positive association between hospital admissions and the daily average concentration of CO was observed. CO is likely to be a risk factor for hospital admissions in adults with asthma.

摘要

背景

哮喘是一种常见的慢性呼吸道疾病，与空气污染暴露有关。然而，只有少数研究集中在空气污染与成人哮喘之间的关系上。此外，这些研究的结果存在争议。因此，本研究旨在分析各种污染物对成人哮喘住院的影响。

方法

本研究共纳入了 2014 年至 2016 年来自中国东北地区的 1019 例非相关住院成人哮喘患者。从 2014 年至 2016 年，从中国国家环境监测中心网站上获取每日平均浓度的空气污染物（<2.5μm 的颗粒物[PM]、<10μm 的颗粒物[PM]、二氧化硫[SO]、二氧化氮[NO]和一氧化碳[CO]）。采用 Cox 逻辑回归分析来分析空气污染物与成人哮喘住院之间的关系。

结果

大多数空气污染物的最大优势比（OR）值出现在滞后日 1 天。选择滞后日 1 天作为暴露期，选择发病前 8 天作为对照期。将三种污染物（PM、CO 和 SO）纳入回归方程，对应的 OR（95%置信区间）分别为 0.995（0.991-0.999）、3.107（1.607-6.010）和 0.979（0.968-0.990）。

结论

观察到住院与 CO 的日平均浓度之间存在正相关关系。CO 可能是成人哮喘住院的危险因素。