天然产物提取与分离技术：全面综述。

Techniques for extraction and isolation of natural products: a comprehensive review.

作者信息

Zhang Qing-Wen, Lin Li-Gen, Ye Wen-Cai

机构信息

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, People's Republic of China.

2Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Provincial Engineering Research Center for Modernization of TCM, College of Pharmacy, Jinan University, Guangzhou, 510632 People's Republic of China.

出版信息

Chin Med. 2018 Apr 17;13:20. doi: 10.1186/s13020-018-0177-x. eCollection 2018.

Natural medicines were the only option for the prevention and treatment of human diseases for thousands of years. Natural products are important sources for drug development. The amounts of bioactive natural products in natural medicines are always fairly low. Today, it is very crucial to develop effective and selective methods for the extraction and isolation of those bioactive natural products. This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products. This paper also presents the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research.