Filip Gabriele, Sala Alessia, Modolo Veronica, Arnoldo Luca, Brunelli Laura, Driul Lorenza
Department of Obstetrics and Gynaecology, ASUFC, Ospedale Santa Maria Della Misericordia, 33100 Udine, Italy.
Department of Medical Area, University of Udine, 33100 Udine, Italy.
Vaccines (Basel). 2024 Apr 17;12(4):427. doi: 10.3390/vaccines12040427.
In the realm of antenatal care, vaccinations serve as a cornerstone, crucial for safeguarding the health of both the mother and the fetus, while also extending protection to the newborn against communicable diseases. Nevertheless, vaccine adherence among pregnant women remains very low. The aim of our study was to evaluate the uptake of vaccines (influence, pertussis, and COVID-19) among women during pregnancy and to understand pregnant women's knowledge of vaccines and the diseases they protect against. The purpose was to investigate the reasons why pregnant women chose not to be vaccinated and to develop effective strategies for informing them about the importance of vaccination for both maternal and fetal safety. prospective observational study was conducted in the Department of Obstetrics and Gynaecology, "Ospedale Santa Maria della Misericordia" in Udine, from 1 December 2021 to 30 June 2022. During this period, a self-completed paper questionnaire was administered to women at the end of pregnancy or during the puerperium. A total of 161 questionnaires were collected. Higher educational level was found to be significantly associated with influenza vaccination uptake ( = 0.037, OR = 2.18, 95% CI 1.05-4.51). Similarly, for pertussis vaccination, adherence was mainly associated with higher educational level ( = 0.014, OR = 2.83, 95% CI 1.24-6.47), but also with Italian nationality ( = 0.003, OR = 3.36, 95% CI 1.56-8.43) and pregnancy attended by a midwife or private gynecologist ( = 0.028, OR = 0.39, 95% CI 0.17-0.90). Regarding the COVID-19 vaccine, the only factor positively influencing uptake was Italian nationality ( = 0.044, OR = 2.66, 95% CI 1.03-6.91). Women's fear that vaccines would endanger the fetus appeared to be the most important reason for refusing vaccinations. Simultaneously, patients also exhibited a desire to receive more information about maternal vaccination, particularly from their general physician or gynecologist. For this reason, it is imperative to enhance maternal vaccination counselling, making it a routine step in prenatal care from the first antenatal visit until the postpartum period.
在产前护理领域，疫苗接种是基石，对于保障母亲和胎儿的健康至关重要，同时也能为新生儿提供针对传染病的保护。然而，孕妇的疫苗接种依从性仍然很低。我们研究的目的是评估孕期女性对疫苗（流感、百日咳和新冠疫苗）的接种情况，并了解孕妇对疫苗及其预防疾病的认知。目的是调查孕妇选择不接种疫苗的原因，并制定有效的策略，告知她们疫苗接种对母婴安全的重要性。2021年12月1日至2022年6月30日，在乌迪内的“慈悲圣母医院”妇产科进行了一项前瞻性观察研究。在此期间，在妊娠末期或产褥期向女性发放了一份自我填写的纸质问卷。共收集到161份问卷。发现较高的教育水平与流感疫苗接种显著相关（P = 0.037，OR = 2.18，95% CI 1.05 - 4.51）。同样，对于百日咳疫苗接种，依从性主要与较高的教育水平相关（P = 0.014，OR = 2.83，95% CI 1.24 - 6.47），但也与意大利国籍（P = 0.003，OR = 3.36，95% CI 1.56 - 8.43）以及由助产士或私人妇科医生护理的妊娠有关（P = 0.028，OR = 0.39，95% CI 0.17 - 0.90）。关于新冠疫苗，唯一对接种有积极影响的因素是意大利国籍（P = 0.044，OR = 2.66，95% CI 1.03 - 6.91）。女性担心疫苗会危及胎儿似乎是拒绝接种疫苗的最重要原因。同时，患者也表现出希望获得更多关于孕产妇疫苗接种的信息，特别是来自她们的全科医生或妇科医生的信息。因此，必须加强孕产妇疫苗接种咨询，使其成为从首次产前检查到产后阶段产前护理的常规步骤。
