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高级别胶质瘤患者的传统及先进磁共振成像

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma.

作者信息

Pope Whitney B, Brandal Garth

机构信息

Department of Radiological Sciences, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA, USA -

Department of Radiological Sciences, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA, USA.

出版信息

Q J Nucl Med Mol Imaging. 2018 Sep;62(3):239-253. doi: 10.23736/S1824-4785.18.03086-8. Epub 2018 Apr 26.

DOI:10.23736/S1824-4785.18.03086-8
PMID:29696946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6123261/
Abstract

Magnetic resonance imaging is integral to the care of patients with high-grade gliomas. Anatomic detail can be acquired with conventional structural imaging, but newer approaches also add capabilities to interrogate image-derived physiologic and molecular characteristics of central nervous system neoplasms. These advanced imaging techniques are increasingly employed to generate biomarkers that better reflect tumor burden and therapy response. The following is an overview of current strategies based on advanced magnetic resonance imaging that are used in the assessment of high-grade glioma patients with an emphasis on how novel imaging biomarkers can potentially advance patient care.

摘要

磁共振成像对于高级别胶质瘤患者的治疗至关重要。通过传统结构成像可以获取解剖细节,但新方法还增加了对中枢神经系统肿瘤图像衍生的生理和分子特征进行探究的能力。这些先进的成像技术越来越多地用于生成能更好反映肿瘤负荷和治疗反应的生物标志物。以下是基于先进磁共振成像的当前策略概述,这些策略用于评估高级别胶质瘤患者,重点介绍新型成像生物标志物如何潜在地推动患者护理的进展。

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