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挪威北部萨米族和非萨米族男性及女性中糖尿病前期和2型糖尿病的患病率——SAMINOR 2临床调查

Prevalence of pre-diabetes and type 2 diabetes mellitus among Sami and non-Sami men and women in Northern Norway - The SAMINOR 2 Clinical Survey.

作者信息

Naseribafrouei Ali, Eliassen Bent-Martin, Melhus Marita, Svartberg Johan, Broderstad Ann Ragnhild

机构信息

a Centre for Sami Health Research, Department of Community Medicine, Faculty of Health Sciences , UiT The Arctic University of Norway , Tromsø , Norway.

b Division of Internal Medicine , University Hospital of North Norway , Tromsø , Norway.

出版信息

Int J Circumpolar Health. 2018 Dec;77(1):1463786. doi: 10.1080/22423982.2018.1463786.

Abstract

The aim of this study was to determine and compare the prevalence of pre-diabetes and type 2 diabetes mellitus (T2DM) among Sami and non-Sami men and women of rural districts in Northern Norway. The SAMINOR 2 Clinical Survey is a cross-sectional population-based study performed in 2012-2014 in 10 municipalities of Northern Norway. A total of 12,455 Sami and non-Sami inhabitants aged 40-79 years were invited to participate and 5878 were included in the analyses. Participants with self-reported T2DM and/or a glycated haemoglobin (HbA1c) result ≥6.5% were categorised as having T2DM. Those with 5.7%≤HbA1c<6.5% were categorised as pre-diabetics. In men, the total age-standardised prevalence of pre-diabetes (37.9% vs 31.4%) and T2DM (10.8% vs 9.5%) were higher in Sami compared with non-Sami; the ethnic difference was statistically significant for both pre-diabetes (OR 1.42, p < 0.001) and T2DM (OR 1.31, p = 0.042). In women, pre-diabetes (36.4% vs 33.5%) and T2DM (8.6% vs 7.0%) were also more common in Sami than non-Sami; the differences in both pre-diabetes (OR 1.20, p = 0.025) and T2DM (OR 1.38, p = 0.021) were also statistically significant. The observed ethnic difference in the waist-to-height ratio (WHtR) was a plausible explanation for the ethnic difference in the prevalence of pre-diabetes and T2DM.

摘要

本研究的目的是确定并比较挪威北部农村地区萨米族和非萨米族男性及女性中糖尿病前期和2型糖尿病(T2DM)的患病率。萨米诺尔2临床调查是一项基于人群的横断面研究,于2012年至2014年在挪威北部的10个自治市进行。共有12455名年龄在40 - 79岁的萨米族和非萨米族居民受邀参与,5878人纳入分析。自我报告患有T2DM和/或糖化血红蛋白(HbA1c)结果≥6.5%的参与者被归类为患有T2DM。HbA1c为5.7%≤HbA1c<6.5%的参与者被归类为糖尿病前期。在男性中,萨米族的糖尿病前期(37.9%对31.4%)和T2DM(10.8%对9.5%)的总年龄标准化患病率高于非萨米族;糖尿病前期(OR 1.42,p < 0.001)和T2DM(OR 1.31,p = 0.042)的种族差异均具有统计学意义。在女性中,糖尿病前期(36.4%对33.5%)和T2DM(8.6%对7.0%)在萨米族中也比非萨米族更常见;糖尿病前期(OR 1.20,p = 0.025)和T2DM(OR 1.38,p = 0.021)的差异也具有统计学意义。观察到的腰高比(WHtR)的种族差异是糖尿病前期和T2DM患病率种族差异的一个合理原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc2/5917894/8522f1f55655/ZICH_A_1463786_F0001_OC.jpg

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