Xu Zhiye, Yu Dan, Yin Xueyao, Zheng Fenping, Li Hong
Department of Endocrinology, The Affiliated Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 310016, Hangzhou, Zhejiang Province, China.
Department of Endocrinology, Zhejiang Hospital, 310013, Hangzhou, Zhejiang Province, China.
Oncotarget. 2017 Jul 4;8(27):44434-44439. doi: 10.18632/oncotarget.17902.
The incidence of diabetes is increasing globally. We investigated the relationship between diabetes prevalence and patient socioeconomic status across multiple countries. We searched PubMed to identify population-based surveys reporting diabetes prevalence between 1990 and May 2016. Search results were filtered, and Human Development Index (HDI) values from the United Nations Development Programme were used to assess socioeconomic status for a given nation. Our analysis included 45 national surveys from 32 countries. Diabetes prevalence was positively correlated with national HDI (r = 0.421 P = 0.041) in developing countries, and negatively correlated with HDI (r = -0.442 P = 0.045) in developed countries. Diabetes prevalence trends were the same in women and men, although men were associated with increased diabetes risk in developed countries (r = 0.459 P = 0.048). Thus, diabetes prevalence rises with increasing HDI in developing countries, and this is reversed in developed countries. Ours is the first study to investigate the relationship between diabetes and socioeconomic status at global level using HDI values. These results will aid in evaluating global diabetes prevalence and risk with respect to patient socioeconomic status, and will be useful in the development of policies that help reduce disease incidence.
全球糖尿病发病率正在上升。我们调查了多个国家糖尿病患病率与患者社会经济地位之间的关系。我们在PubMed上进行搜索，以确定报告1990年至2016年5月期间糖尿病患病率的基于人群的调查。对搜索结果进行筛选，并使用联合国开发计划署的人类发展指数（HDI）值来评估特定国家的社会经济地位。我们的分析纳入了来自32个国家的45项全国性调查。在发展中国家，糖尿病患病率与国家HDI呈正相关（r = 0.421，P = 0.041），而在发达国家则与HDI呈负相关（r = -0.442，P = 0.045）。糖尿病患病率趋势在男性和女性中相同，尽管在发达国家男性患糖尿病的风险增加（r = 0.459，P = 0.048）。因此，在发展中国家，糖尿病患病率随HDI的增加而上升，而在发达国家则相反。我们是第一项使用HDI值在全球层面研究糖尿病与社会经济地位之间关系的研究。这些结果将有助于评估全球糖尿病患病率以及与患者社会经济地位相关的风险，并将有助于制定有助于降低疾病发病率的政策。
