Michalsen Vilde L, Braaten Tonje, Kvaløy Kirsti, Melhus Marita, Broderstad Ann R
Centre for Sami Health Research, Department of Community Medicine UiT The Arctic University of Norway Tromsø Norway.
Department of Community Medicine UiT The Arctic University of Norway Tromsø Norway.
Obes Sci Pract. 2020 Feb 3;6(3):324-339. doi: 10.1002/osp4.404. eCollection 2020 Jun.
The relationships between metabolic markers and obesity measures may differ by ethnicity, sex, and height. Questions have been posed whether these relationships differ by ethnicity in the population in Northern Norway, but this has not been explored yet.
Investigate the relationships between metabolic markers and obesity measures in Sami and non-Sami and explore the impact of stature.
In total, 13 921 men and women aged 30 and 36 to 79 years (22.0% Sami) from a population-based cross-sectional survey in Norway, the SAMINOR 1 Survey (2003-2004, 57.2% attendance), were included. Relationships between triglycerides, high-density lipoprotein cholesterol, glucose, systolic/diastolic blood pressure (BP), metabolic syndrome and diabetes mellitus as outcomes, and body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR), respectively, were modelled using fractional polynomial regression. Appropriate interaction analyses and adjustments were made.
The non-Sami were approximately 6 cm taller than the Sami. No interactions were found between ethnicity and obesity. At the same levels of WC, BMI, or WHtR, levels of lipids and BP differed marginally between Sami and non-Sami, but these were eliminated by height adjustment, with one exception: At any given WC, BMI, or WHtR, Sami had approximately 1.4 mmHg (95% CI, -2.1 to -0.7) lower systolic BP than non-Sami ( values < .001).
Height explained the marginal ethnic differences in metabolic markers at the same level of obesity, except for systolic BP, which was lower in Sami than in non-Sami at any given BMI, WC, or WHtR.
代谢标志物与肥胖指标之间的关系可能因种族、性别和身高而有所不同。挪威北部人群中这些关系是否因种族而异，这一问题虽已提出，但尚未得到研究。
研究萨米族和非萨米族人群中代谢标志物与肥胖指标之间的关系，并探讨身高的影响。
纳入了来自挪威一项基于人群的横断面调查（即萨米诺尔1调查，2003 - 2004年，应答率57.2%）的13921名年龄在30岁以及36至79岁的男性和女性（其中22.0%为萨米族）。分别以甘油三酯、高密度脂蛋白胆固醇、血糖、收缩压/舒张压、代谢综合征和糖尿病作为结局指标，以体重指数（BMI）、腰围（WC）和腰高比（WHtR）作为暴露因素，采用分数多项式回归模型进行分析。进行了适当的交互分析和调整。
非萨米族比萨米族高约6厘米。未发现种族与肥胖之间存在交互作用。在相同的WC、BMI或WHtR水平下，萨米族和非萨米族的血脂和血压水平略有差异，但经身高调整后这些差异消失，只有一个例外：在任何给定的WC、BMI或WHtR水平下，萨米族的收缩压比非萨米族低约1.4 mmHg（95%可信区间，-2.1至-0.7）（P值<0.001）。
在相同肥胖水平下，身高解释了代谢标志物中存在的微小种族差异，但收缩压除外，在任何给定的BMI、WC或WHtR水平下，萨米族的收缩压均低于非萨米族。
