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脊髓损伤男性使用电射精辅助生育——文献综述

Assisted fertility using electroejaculation in men with spinal cord injury--a review of literature.

作者信息

Chung P H, Yeko T R, Mayer J C, Sanford E J, Maroulis G B

机构信息

Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa 33606, USA.

出版信息

Fertil Steril. 1995 Jul;64(1):1-9.

PMID:7789540
Abstract

OBJECTIVE

To review the effectiveness of rectal probe electroejaculation in terms of pregnancy in treatment of anejaculatory males due to spinal cord injury. The characteristics of electroejaculates also are examined.

DATA IDENTIFICATION

All English language studies reporting pregnancies as a result of electroejaculation from men with spinal cord injury and related publications on electroejaculation were identified through MEDLINE search and manual scanning of recent relevant journals.

RESULTS

Electroejaculation has become an accepted mode of semen procurement in anejaculatory individuals, with a success rate of approximately 60% to 90% varying among different centers. In general these electroejaculates exhibit high sperm counts but low motility and poor sperm function. Retrograde ejaculation is also common. Pregnancies using electroejaculates have been documented since 1975 in the form of case reports and small series. Assisted reproductive technology recently has been used in conjunction with electroejaculation. Although results are encouraging, pregnancy rates, however, cannot be accurately estimated because of the lack of large series in the literature.

CONCLUSIONS

An increasing number of spinal cord-injured patients desiring fertility can achieve pregnancy through combined use of electroejaculation and assisted reproductive techniques. Larger series are needed to establish an accurate pregnancy rate. Elucidation by further studies on etiology of sperm dysfunction of these individuals may improve their prognosis.

摘要

目的

回顾直肠探头电射精在脊髓损伤所致无射精男性患者妊娠方面的有效性。同时也研究电射精精液的特征。

资料识别

通过医学文献数据库检索及手动查阅近期相关期刊,识别出所有报道脊髓损伤男性患者电射精后妊娠情况的英文研究以及关于电射精的相关出版物。

结果

电射精已成为无射精个体获取精液的一种公认方式,不同中心的成功率约为60%至90%。总体而言,这些电射精精液显示精子数量多,但活力低且精子功能差。逆行射精也很常见。自1975年以来,已有以病例报告和小样本系列形式记录的使用电射精精液妊娠的情况。辅助生殖技术最近已与电射精联合使用。尽管结果令人鼓舞,但由于文献中缺乏大样本系列研究,妊娠率无法准确估计。

结论

越来越多希望生育的脊髓损伤患者可通过联合使用电射精和辅助生殖技术实现妊娠。需要更大样本系列研究来确定准确的妊娠率。进一步研究这些个体精子功能障碍的病因可能会改善其预后。

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