Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Research Institute, Optics Laboratory, Topcon Corporation, Tokyo, Japan.
Invest Ophthalmol Vis Sci. 2014 May 29;55(6):3905-11. doi: 10.1167/iovs.14-14391.
We investigated higher-order aberrations (HOAs) of the anterior and posterior corneal surfaces in patients with keratectasia after LASIK.
The subjects comprised four groups: 12 eyes with keratectasia after LASIK, 30 eyes following LASIK without keratectasia, 30 keratoconic eyes, and 30 normal eyes. Corneal HOAs due to the anterior and posterior corneal surfaces for 6-mm pupils (root mean square [μm]) were obtained using a Scheimpflug-based corneal tomographer and compared among the four groups.
There were significant differences in total HOAs of the anterior and posterior corneal surfaces (mean ± SD) in the keratectasia (2.49 ± 1.37 and 0.83 ± 0.57), keratoconus (4.50 ± 2.57 and 1.18 ± 0.65), LASIK (0.84 ± 0.25 and 0.14 ± 0.04), and normal (0.52 ± 0.15 and 0.17 ± 0.06) groups except for between keratoconus and keratectasia at the posterior surface. Keratectasia and keratoconus showed similar coma-dominant patterns at both surfaces, and there were no significant differences in the Zernike terms between both groups except for the total HOAs and coma aberration at the anterior surface.
Although flap creation and laser ablation were supposed to center on the primary line of sight in LASIK, keratectasia after LASIK showed coma-dominant HOAs at both corneal surfaces. This suggests that the cornea in keratectasia has optical properties similar to those in keratoconus.
我们研究了 LASIK 术后角膜扩张患者的前、后角膜表面的高阶像差(HOAs)。
研究对象包括 4 组:12 只 LASIK 术后角膜扩张眼,30 只 LASIK 术后无角膜扩张眼,30 只圆锥角膜眼和 30 只正常眼。使用基于 Scheimpflug 的角膜断层扫描仪获得 6mm 瞳孔的前、后角膜表面的角膜 HOAs(均方根[μm]),并在这 4 组之间进行比较。
角膜扩张组(前、后表面的总 HOAs 分别为 2.49 ± 1.37μm 和 0.83 ± 0.57μm)、圆锥角膜组(4.50 ± 2.57μm 和 1.18 ± 0.65μm)、LASIK 组(0.84 ± 0.25μm 和 0.14 ± 0.04μm)和正常组(0.52 ± 0.15μm 和 0.17 ± 0.06μm)的前、后角膜表面的总 HOAs 存在显著差异,除了后表面的圆锥角膜组和角膜扩张组之间没有差异。角膜扩张组和圆锥角膜组在两个表面都表现出彗差主导的模式,除了前表面的总 HOAs 和彗差像差之外,两组的泽尼克项之间没有显著差异。
尽管 LASIK 术中的瓣制作和激光消融应该以主视线为中心,但 LASIK 术后的角膜扩张在两个角膜表面都表现出彗差主导的 HOAs。这表明角膜扩张的角膜具有与圆锥角膜相似的光学特性。