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动态Scheimpflug分析仪的测量重复性

Measurement repeatability of the dynamic Scheimpflug analyzer.

作者信息

Miki Atsuya, Maeda Naoyuki, Asai Tomoko, Ikuno Yasushi, Nishida Kohji

机构信息

Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, Japan.

出版信息

Jpn J Ophthalmol. 2017 Nov;61(6):433-440. doi: 10.1007/s10384-017-0534-9. Epub 2017 Oct 5.

DOI:10.1007/s10384-017-0534-9
PMID:28983780
Abstract

PURPOSE

To evaluate the repeatability of corneal deformation parameters measured using a dynamic Scheimpflug analyzer and the impact of baseline clinical factors on the repeatability of each parameter.

STUDY DESIGN

Retrospective, cross-sectional study.

METHODS

Forty-eight eyes (48 healthy subjects; mean age, 49.0 ± 19.5 years) underwent repeated examinations with the Scheimpflug analyzer to evaluate the test-retest variability. The intraclass correlation coefficient (ICC) and repeatability coefficient as indicators of variability were computed for 35 parameters measured with the Scheimpflug analyzer. The associations between the magnitude of the test-retest variability and baseline factors, such as age, axial length (AL), intraocular pressure (IOP), and central corneal thickness (CCT), were analyzed.

RESULTS

The test-retest repeatability was excellent for 22 (62.9%) of 35 parameters (ICC ≥ 0.75), good for seven (20%), (ICC ≥ 0.6), fair for four (11.4%), (ICC ≥ 0.4), and poor for two (5.7%) parameters (ICC < 0.4). Age was associated positively with the magnitude of variability in 13 (37.1%) parameters; measurement variability was affected significantly by AL (5 parameters, 14.3%) and CCT (7 parameters, 20%) but, except for one parameter not by IOP.

CONCLUSION

Most parameters of the dynamic Scheimpflug analyzer showed favorable measurement reliability in healthy subjects. However, six parameters showed poor-to-fair repeatability. Age, AL, and CCT significantly affected the repeatability of several parameters. These results should be considered when clinicians use this device in clinical practice.

摘要

目的

评估使用动态Scheimpflug分析仪测量角膜变形参数的可重复性,以及基线临床因素对各参数可重复性的影响。

研究设计

回顾性横断面研究。

方法

48只眼(48名健康受试者;平均年龄49.0±19.5岁)使用Scheimpflug分析仪进行重复检查,以评估重测变异性。计算了Scheimpflug分析仪测量的35个参数的组内相关系数(ICC)和作为变异性指标的重复性系数。分析了重测变异性大小与年龄、眼轴长度(AL)、眼压(IOP)和中央角膜厚度(CCT)等基线因素之间的关联。

结果

35个参数中有22个(62.9%)的重测可重复性极佳(ICC≥0.75),7个(20%)良好(ICC≥0.6),4个(11.4%)尚可(ICC≥0.4),2个(5.7%)较差(ICC<0.4)。13个(37.1%)参数的变异性大小与年龄呈正相关;测量变异性受AL(5个参数,14.3%)和CCT(7个参数,20%)显著影响,但除一个参数外不受IOP影响。

结论

动态Scheimpflug分析仪的大多数参数在健康受试者中显示出良好的测量可靠性。然而,6个参数的可重复性较差至尚可。年龄、AL和CCT显著影响了几个参数的可重复性。临床医生在临床实践中使用该设备时应考虑这些结果。

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Jpn J Ophthalmol. 2016 Sep;60(5):357-64. doi: 10.1007/s10384-016-0457-x. Epub 2016 Jun 20.
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