Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Clin Gastroenterol Hepatol. 2019 Jan;17(1):200-202.e1. doi: 10.1016/j.cgh.2018.04.035. Epub 2018 Apr 24.
Candida infection in the gastrointestinal tract is most studied in immunocompromised patients. Patients without systemic immunodeficiency, however, may have esophageal candidiasis associated with antibiotic or steroid medication use, alcoholic consumption, diabetes mellitus, and esophageal stasis disorders such achalasia or scleroderma esophagus. This population has not been well studied. We aim to describe demographics, risk factors, and relevant clinical outcomes for patients with Candida esophagitis with an emphasis in systemically immunocompetent patients.
胃肠道念珠菌感染在免疫功能低下的患者中研究最多。然而,没有全身免疫缺陷的患者可能因使用抗生素或皮质类固醇药物、酒精摄入、糖尿病和食管淤滞性疾病(如贲门失弛缓症或硬皮病食管)而出现食管念珠菌病。这一人群尚未得到充分研究。我们旨在描述念珠菌性食管炎患者的人口统计学、危险因素和相关临床结果,重点关注系统免疫功能正常的患者。