Anderson Katie L, Tefft Karen M
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
J Vet Intern Med. 2025 Jul-Aug;39(4):e70184. doi: 10.1111/jvim.70184.
Esophageal candidiasis is the most common cause of infectious esophagitis in human patients, but to date, this disease has not been reported in companion animals. A 16-month-old male intact King Shepherd dog and a 2-year-old female spayed German Shepherd dog were presented for evaluation of chronic regurgitation with diffuse megaesophagus identified on thoracic radiographs. In both cases, esophagoscopy disclosed diffuse, white fungal plaques, and brush cytology showed severe esophagitis with numerous yeast structures. Fungal cultures in both cases were positive for Candida albicans. The dogs were treated with fluconazole, which led to improvement or resolution of esophageal candidiasis. Esophagoscopy to evaluate for candidiasis should be considered in dogs with megaesophagus that either fail to improve on medical management or suffer an exacerbation of previously controlled signs.
食管念珠菌病是人类患者感染性食管炎最常见的病因，但迄今为止，这种疾病在伴侣动物中尚未见报道。一只16个月大的未绝育雄性德国牧羊犬和一只2岁已绝育的雌性德国牧羊犬因慢性反流前来就诊，胸部X光片显示有弥漫性巨食管症。在这两个病例中，食管镜检查均发现弥漫性白色真菌斑块，刷片细胞学检查显示严重食管炎并有大量酵母样结构。两个病例的真菌培养白色念珠菌均呈阳性。这两只狗接受了氟康唑治疗，食管念珠菌病得到改善或治愈。对于患有巨食管症且药物治疗无效或先前控制的症状加重的犬只，应考虑进行食管镜检查以评估是否存在念珠菌病。
