巴戟天汁对 2 型糖尿病患者代谢因素和氧化应激的影响：一项随机临床试验。
The barberry juice effects on metabolic factors and oxidative stress in patients with type 2 diabetes: A randomized clinical trial.
机构信息
Babol University of Medical Sciences, Babol, Iran.
Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Complement Ther Clin Pract. 2018 May;31:170-174. doi: 10.1016/j.ctcp.2018.01.009. Epub 2018 Feb 17.
AIM
The aim of this study was to investigate the effect of barberry juice (BJ) on cardiovascular risk factors in patients with type 2 diabetes (T2DM).
METHODS
46 diabetic Patients were randomly allocated to either the BJ group (n = 23) who consumed 200 ml of BJ daily for eight weeks, or the control group (n = 23) with no intervention. At the baseline and the end of 8-week intervention, blood pressure and biochemical markers were measured.
RESULTS
forty-two Patients completed the study. After intervention systolic blood pressure (SBP), diastolic blood pressure (DBP), Fasting Blood Sugar (FBS) Total Cholesterol significantly decreased (P < 0.05 for treatment effect) also Triglyceride (TG) decrease significantly in BJ group. Paraoxonase-1(PON1) concentrations significantly increased in Bj group and have a significant difference (P < 0.0001 for treatment effect) compared with control group.
CONCLUSIONS
This study revealed that BJ might decrease the risk of cardiovascular diseases in patients with diabetes.
目的
本研究旨在探讨小檗汁（BJ）对 2 型糖尿病（T2DM）患者心血管危险因素的影响。
方法
46 例糖尿病患者随机分为 BJ 组（n=23）和对照组（n=23），BJ 组每天饮用 200ml BJ，干预 8 周。在基线和 8 周干预结束时，测量血压和生化标志物。
结果
42 例患者完成了研究。干预后，收缩压（SBP）、舒张压（DBP）、空腹血糖（FBS）、总胆固醇明显降低（治疗效果 P<0.05），BJ 组甘油三酯（TG）也明显降低。BJ 组对氧磷酶-1（PON1）浓度明显升高，与对照组相比差异有统计学意义（治疗效果 P<0.0001）。
结论
本研究表明，BJ 可能降低糖尿病患者患心血管疾病的风险。
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