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罗哌卡因在口腔阿弗他溃疡治疗中的应用。

The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis.

机构信息

UOC Maxillo Facial Surgery, Policlinico Gemelli Foundation, Catholic University Medical School, Rome, Italy.

Department of Anesthesiology and Intensive Care Medicine, Policlinico Gemelli Foundation, Catholic University Medical School, Rome, Italy.

出版信息

Biomed Res Int. 2018 Mar 11;2018:1868254. doi: 10.1155/2018/1868254. eCollection 2018.

Abstract

The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients' part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives.

摘要

在口腔阿弗他溃疡的治疗中使用麻醉药物是医生可以使用的药物治疗可能性之一,用于治疗最疼痛的形式。通常,使用利多卡因或双氯芬酸来治疗这种疾病,但它们的使用时间非常有限,因此实际用途不大。在这项研究中,作者使用了罗哌卡因,其药物动力学使镇痛作用能够持续 60 至 90 分钟。在我们的研究中,我们比较了 8 组接受 3 种主要药物产品的患者:一组给予麻醉药物,一组给予局部用药,常用于治疗口疮性病变,最后一组给予多种维生素。这些药物产品单独使用和以各种可能的组合用于 8 组。这项研究的结果非常有趣,表明在使用麻醉药物的所有组中,患者的满意度更高,因为他们的疼痛水平在第一次用药后就变得更容易控制,并且患者可以继续正常生活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e62/5866890/9654a6a15de1/BMRI2018-1868254.001.jpg

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