Lin Guanquan, Chen Huayao, Zhou Hongjun, Zhou Xinhua, Xu Hua
School of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Guangzhou Key Lab for Efficient Use of Agricultural Chemicals, Guangzhou 510225, China.
Materials (Basel). 2018 May 1;11(5):710. doi: 10.3390/ma11050710.
Using butyl methacrylate (BMA) and styrene (St) as monomers and divinylbenzene (DVB) as a crosslinking agent, P(St-BMA) microspheres were prepared by suspension polymerization. Tea tree oil (TTO) microspheres were prepared by adsorbing TTO on P(St-BMA) microspheres. The structure and surface morphology of P(St-BMA) microspheres and TTO microspheres were characterized by Fourier transformed infrared spectroscopy (FTIR), optical microscopy, and Thermogravimetric analysis (TGA). In doing so, the structural effect of P(St-BMA) microspheres on oil absorption and sustained release properties could be investigated. The results show that the surface of the P(St-BMA) microspheres in the process of TTO microsphere formation changed from initially concave to convex. The TTO microspheres significantly improved the stability of TTO, which was found to completely decompose as the temperature of the TTO increased from about 110 °C to 150 °C. The oil absorption behavior, which was up to 3.85 g/g, could be controlled by adjusting the monomer ratio and the amount of crosslinking agent. Based on Fickian diffusion, the sustained release behavior of TTO microspheres was consistent with the Korsmeyer-Pappas kinetic model. After 13 h of natural release, the anti-bacterial effect of the TTO microspheres was found to be significantly improved compared to TTO.
以甲基丙烯酸丁酯（BMA）和苯乙烯（St）为单体，二乙烯基苯（DVB）为交联剂，通过悬浮聚合法制备了P（St-BMA）微球。通过将茶树油（TTO）吸附在P（St-BMA）微球上制备了TTO微球。采用傅里叶变换红外光谱（FTIR）、光学显微镜和热重分析（TGA）对P（St-BMA）微球和TTO微球的结构和表面形貌进行了表征。通过这样做，可以研究P（St-BMA）微球对吸油和缓释性能的结构影响。结果表明，在TTO微球形成过程中，P（St-BMA）微球的表面从最初的凹形变为凸形。TTO微球显著提高了TTO的稳定性，发现随着TTO温度从约110℃升高到150℃，TTO完全分解。吸油行为可达3.85 g/g，可通过调节单体比例和交联剂用量来控制。基于菲克扩散，TTO微球的缓释行为符合Korsmeyer-Pappas动力学模型。自然释放13小时后，发现TTO微球的抗菌效果比TTO显著提高。
